What is meant by an atypical antipsychotic drug?

Atypical antipsychotics are antipsychotics that are less likely than traditional antipsychotics to cause certain side effects, such as extrapyramidal symptoms (EPS).

What do atypical drugs do?

Atypical antipsychotics are a class of drugs used primarily to treat psychotic disorders. Rationale for use includes relief from symptoms such as hallucinations, delusions or abnormal behaviour/thought, and sedative and tranquillising effects in very disturbed or aggressive patients.

What is the action of atypical antipsychotics?

Conclusion: Atypicals clinically help patients by transiently occupying D2 receptors and then rapidly dissociating to allow normal dopamine neurotransmission. This keeps prolactin levels normal, spares cognition, and obviates EPS.

What do antipsychotic drugs do?

Antipsychotic drugs don’t cure psychosis but they can help to reduce and control many psychotic symptoms, including: delusions and hallucinations, such as paranoia and hearing voices. anxiety and serious agitation, for example from feeling threatened. incoherent speech and muddled thinking.

What is the meaning of antipsychotics?

Definition of antipsychotic : any of the powerful tranquilizers (such as the phenothiazines and butyrophenones) used especially to treat psychosis and believed to act by blocking dopamine nervous receptors. — called also neuroleptic.

What is the difference between typical and atypical drugs?

Typical antipsychotic drugs act on the dopaminergic system, blocking the dopamine type 2 (D2) receptors. Atypical antipsychotics have lower affinity and occupancy for the dopaminergic receptors, and a high degree of occupancy of the serotoninergic receptors 5-HT2A.

How do atypical antipsychotics work psychology?

Atypical antipsychotics such as Clozapine bind to dopamine, serotonin and glutamate receptors. Atypical antipsychotic drugs work on negative symptoms, improving mood, cognitive functions and reducing depression and anxiety. They also have some effect on other neurotransmitters such as serotonin.

What is the benefit of atypical antipsychotic medications?

Atypical antipsychotic drugs offer several notable benefits over typical antipsychotics, including greater improvement in negative symptoms, cognitive function, prevention of deterioration, and quality of life, and fewer extrapyramidal symptoms (EPS).

What are examples of atypical antipsychotics?


  • Clozapine.
  • Risperidone.
  • Olanzapine.
  • Quetiapine.
  • Ziprasidone.
  • Aripiprazole.

What do antipsychotics do in the brain?

Antipsychotics reduce or increase the effect of neurotransmitters in the brain to regulate levels. Neurotransmitters help transfer information throughout the brain. The neurotransmitters affected include dopamine, noradrenaline, and serotonin.

How do atypical antipsychotics affect violent behavior?

In a prospective study of patients with schizophrenia,27 treatment with atypical antipsychotic medications, including clozapine, risperidone, and olanzapine, significantly reduced violent behavior, whereas treatment with conventional neuroleptics did not significantly reduce violence.

What is antipsychotic drug explain with example?

Antipsychotic: A medication (or another measure) that is believed to be effective in the treatment of psychosis. For example, aripiprazole (Abilify) is an antipsychotic medication used to treat schizophrenia.