What is Osler-Weber-Rendu syndrome?

HHT; Osler-Weber-Rendu syndrome; Osler-Weber-Rendu disease; Rendu-Osler-Weber syndrome. Hereditary hemorrhagic telangiectasia (HHT) is an inherited disorder of the blood vessels that can cause excessive bleeding. Blood used by the body is brought back to the heart and lungs by the veins of the body.

What causes Osler-Weber-Rendu syndrome?

What Causes Osler-Weber-Rendu Syndrome? People with OWR inherit an abnormal gene that causes their blood vessels to form incorrectly. OWR is an autosomal dominant disorder. This means that only one parent needs to have the abnormal gene to pass it on to their children.

Is Osler-Weber-Rendu syndrome curable?

Treatment. There is no cure for hereditary hemorrhagic telangiectasia. Treatment for the condition generally is focused on managing the symptoms. Nosebleeds are managed through the use of humidifiers, nasal lubrication or applying pressure to the affected area.

Is Osler-Weber-Rendu a bleeding disorder?

Osler-Weber-Rendu disease (OWRD) is a rare autosomal dominant disorder that affects blood vessels throughout the body (causing vascular dysplasia) and results in a tendency for bleeding. (The condition is also known as hereditary hemorrhagic telangiectasia [HHT]; the two terms are used interchangeably in this article.)

Is HHT life threatening?

Men, women, and children from all racial and ethnic groups can be affected by HHT and experience the problems associated with this disorder, some of which are serious and potentially life-threatening. Fortunately, if HHT is discovered early, effective treatments are available. However, there is no cure for HHT.

Does HHT get worse with age?

HHT-related GI bleeding risk increases with age. Telangiectasia in the GI tract do not cause pain.

Is hereditary hemorrhagic telangiectasia painful?

HHT-related GI bleeding risk increases with age. Telangiectasia in the GI tract do not cause pain. Symptoms of GI bleeding include black or bloody stool and/or anemia.

Is Osler Weber Rendu syndrome rare?

Osler-Weber-Rendu disease, also known as hereditary hemorrhagic telangiectasia, is a rare autosomal dominant condition causing systemic fibrovascular dysplasia. It has an incidence of 1-2/100,000.

What foods to avoid when you have HHT?

Avoid certain foods. In some people, HHT nosebleeds are triggered when they consume blueberries, red wine, dark chocolate or spicy foods. You might want to keep a food diary to see if there’s any connection between what you eat and the severity of your nosebleeds.

Can you cure HHT?

Most major manifestations of HHT, including AVMs and ruptured telangiectases, are very treatable. They cannot yet be prevented and HHT cannot yet be cured, but the options for treatment allow HHT patients to live normal lives.

Is HHT serious?

Can HHT skip a generations?

HHT is an autosomal dominant (it does not skip a generation), genetic blood vessel disorder that causes bleeding in multiple organs of the body.