Can Accutane have permanent mental effects?

Isotretinoin has been associated with psychiatric disorders and symptoms beyond depression and psychosis in some cases. In 1 instance, a 23-year-old man developed obsessive-compulsive disorder after 7 years of isotretinoin treatment (10–20 mg/d).

Can Accutane cause permanent depression?

While isotretinoin, used to treat acne vulgaris, has not been demonstrated to be associated with depression or suicide, the possibility of a relatively rare idiosyncratic adverse effect remains.

Can Accutane give you psychosis?

Isotretinoin is a synthetic oral retinoid, which is effective against severe, recalcitrant, nodulocystic acne. Since it entered the market, it has been associated with a variety of adverse psychiatric effects, including depression, psychosis, mood swings, violent behaviour, suicide and suicide attempts (1).

What are the mental side effects of Accutane?

A number of cases of neuropsychiatric side effects including depression, suicidality, violence, aggression, anxiety and psychosis have been associated with isotretinoin use with evidence for a causal rol. Isotretinoin use has declined in recent years but considerable caution is needed in its use.

Can Accutane cause bipolar disorder?

Dermatologists may not have been aware of the occurrence of psychiatric disorders. There is strong evidence from the psychiatric literature that demonstrates an association of isotretinoin to depression, probable clinical exacerbation of bipolar mood disorder and possible links to psychosis.

Can Accutane affect your brain?

Five patients taking isotretinoin reported headaches and irritability or mood changes; all five had decreased brain metabolism, the greatest decreases in those who developed headaches.

Can Accutane cause schizophrenia?

More recently, isotretinoin treatment, schizophrenia, and depression have each been associated with elevated homocysteine levels, indicating the possibility that isotretinoin-induced homocysteine elevation may contribute to psychiatric side effects.

Can Accutane cause brain damage?

Pressure on your brain Rarely, isotretinoin can cause increased pressure on the brain. This can lead to permanent loss of eyesight and, in rare cases, death. Stop taking isotretinoin and call your doctor right away if you have any of these symptoms: severe headache.

Can Accutane cause social anxiety?

Social anxiety is common in acne patients and the effects of isotretinoin treatment on social anxiety symptoms have not yet been thoroughly investigated.

Does Accutane cause anger issues?

WASHINGTON — A drug with proven benefit in the treatment of severe acne is under scrutiny again after the Food and Drug Administration said the drug, Accutane, may be linked to aggression and violent behavior in some users.

Can Accutane cause bipolar?

There is strong evidence from the psychiatric literature that demonstrates an association of isotretinoin to depression, probable clinical exacerbation of bipolar mood disorder and possible links to psychosis.