What is meropenem indication?

Wide spectrum antibiotic used to treat both Gram-positive and Gram-negative infections including pseudomonas spp. resistant to other antibiotics. Use to treat infections like meningitis, pneumonia and intra-abdominal infections, complicated skin/skin structure infections.

Is meropenem used for pneumonia?

This study demonstrates that meropenem monotherapy is effective and well tolerated for patients with hospital-acquired pneumonia, including a subgroup of patients with ventilator-associated pneumonia.

Is meropenem used to treat sepsis?

Meropenem, a member of the carbapenem class, is widely used as empirical therapy in the treatment of sepsis and septic shock regarding its broad-spectrum activity and a low toxicity profile. The PD of meropenem is a time-dependent activity, similar to other beta-lactam antibiotics.

What type of bacteria does meropenem treat?

Meropenem is a broad-spectrum carbapenem antibiotic that possesses excellent activity against both aerobic Gram-positive and aerobic Gram-negative bacteria, and also covers common anaerobes.

What infections is meropenem used to treat?

Meropenem injection is used to treat skin and abdominal (stomach area) infections caused by bacteria and meningitis (infection of the membranes that surround the brain and spinal cord) in adults and children 3 months of age and older.

What bacteria does meropenem cover?

Does meropenem cover E coli?

Meropenem and imipenem both exhibited excellent activity against E. coli and Klebsiella spp., and, of the range of antimicrobial agents tested, were shown to have the highest susceptibility rates.

Does meropenem affect kidney?

Importantly, meropenem-related seizures were rare (0.1%), even in patients with renal impairment. In summary, meropenem has an excellent safety profile and is therefore suitable for use in elderly and/or renally impaired patients.

Does meropenem treat UTI?

Meropenem and vaborbactam injection is used to treat serious urinary tract infections, including kidney infections, that are caused by bacteria. Meropenem is in a class of medications called carbapenem antibiotics.

Does meropenem cover C diff?

In patients hospitalized with severe infections who require anti-Pseudomonal coverage, the available data suggests that penicillins (such as piperacillin/tazobactam) may have a lower risk of C difficile infection versus cephalosporins (such as cefepime) or carbapenems (such as meropenem).