What does a progesterone level of 17 mean?

High levels of 17-OH progesterone can indicate a condition called congenital adrenal hyperplasia (CAH). CAH is a glandular disorder that results in the adrenal glands being unable to create sufficient cortisol, and it may increase the production of male sex hormones called androgens.

Does 17-hydroxyprogesterone increase in pregnancy?

The adrenal glands, ovaries, testes, and placenta produce 17-hydroxyprogesterone. 17-HO-P increases in the third trimester of pregnancy. 17-HO-P is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids, androgens and estrogens.

What is a high level of 17-OHP?

In infants with CAH, the 17-OHP level ranges from 2,000 to 40,000 ng/dL or 60.6 to 1212 nmol/L. In adults, a level greater than 200 ng/dL or 6.06 nmol/L may be due to nonclassical adrenal hyperplasia.

Why is my 17-hydroxyprogesterone high?

If results show high levels of 17-OHP, it’s likely you or your child has CAH. Usually, very high levels means a more severe form of the condition, while moderately high levels usually means a milder form. If you or your child is being treated for CAH, lower levels of 17-OHP may mean the treatment is working.

What is a good progesterone level for 4 weeks pregnant?

Progesterone levels also can have quite a variance at this stage of pregnancy. They can range from 9-47ng/ml in the first trimester, with an average of 12-20ng/ml in the first 5-6 weeks of pregnancy.

What are normal 17 hydroxyprogesterone levels in female?

Less than 220 nanograms per deciliter in adult males. Less than 100 nanograms per deciliter in prepubertal females. Less than 51 nanograms per deciliter in females after menopause.

What is the difference between progesterone and 17-hydroxyprogesterone?

17-OHPC is currently recommended for the prevention of preterm birth in women with a singleton gestation and a history of preterm birth. Vaginal progesterone is recommended for the prevention of preterm birth in women with a short cervix (with or without a history of preterm birth).

What does low 17-hydroxyprogesterone mean in adults?

Low values of 17-OHP are found in adrenal hypofunction, whether of adrenal or hypothalamic/pituitary origin. The most frequent cause of a low 17-OHP concentration is suppression of the pituitary–adrenal axis by synthetic glucocorticoids given therapeutically.

When do you check 17-OHP?

The 17-OHP test is ordered routinely as part of a newborn screen and may be repeated if the screening test is elevated in order to confirm the initial results. A 17-OHP test may be ordered when an infant or young child has signs and symptoms of adrenal insufficiency or of CAH.

What should progesterone be at 6 weeks pregnant?

What should my progesterone level be at 7 weeks?

It increases thereafter from gestation weeks 7–9 (mean serum progesterone in week 7 = 63.4 nmol/L, compared to 67.7 nmol/L in week 8 (p = 0.374) and 78.9 nmol/L in week 9 (p < 0.001).