Is HFA 134a A refrigerant?

HFA 134a (also known as R134a) is used as an automobile air conditioner refrigerant, but because it has a global warming potential (GWP) of 1410, is likely to be withdrawn from use, as only compounds with a GWP of less than 150 will be allowed.

What is HFA 134a used for?

HFA 134a (1,1,1,2-tetrafluoroethane) is a ‘non-ozone depleting’ candidate for use as a drug propellant in multi-dose inhalers (MDIs). A means for assuring the safety of such a compound for human use is to check mat there is no excessive or unexpected accumulation in the body and selected regions.

Is pMDI same as MDI?

Pressurized metered-dose inhalers (pMDI) are a type of MDIs that works based on the pressurized propellant in the aerosol chamber. The advantage of MDIs is the accurate and repeatable dosing, which minimizes the errors.

How do you measure R134a viscosity?

earliest R134a viscosity measurements were carried out by Shanklandet al. [9] in a viscometer with a coiled capillary. These results deviate from the correlation systematically up to a maximum of 33% at 1000kg-m -3 (343.15 K).

Does HFA 134a irritate the skin?

When HFA 134a is in contact with cutaneous or ocular mucosal membranes it causes slight irritation possibly due to evaporation. It does not sensitize the skin.

Is Freon 134a as stable as CFC-12?

As the CFC-12/mineral oil combinations have been proven in actual service, these tests indicate that Freon™ 134a/ PAG and Freon™ 134a/POE solutions have acceptable chemical stability. In several other tests, results have confirmed that the Freon™ 134a molecule is as chemically stable as CFC-12.

What is the half life of HFA 134a 19F NMR?

The HFA-134a 19F NMR signal disappeared rapidly following removal of the test atmosphere, with an elimination half-life of 4.6 +/- 0.6 min in the male rats and 4.9 +/- 1.5 min in the female rats. The safety and pharmacokinetics of HFC 134a and HFC 227 were assessed in two separate double-blind studies.