What is oxsoralen used for?

This medication is used along with controlled ultraviolet light (UVA) to help control severe psoriasis. It may also be used for other skin conditions (vitiligo, cutaneous T-cell lymphoma-CTCL). Methoxsalen works by making the skin more sensitive to UVA light.

What type of drug is Methoxsalen?

FuranocoumarinMethoxsalen / ClassificationThe furanocoumarins, or furocoumarins, are a class of organic chemical compounds produced by a variety of plants. Most of the plant species found to contain furanocoumarins belong to a handful of plant families. Wikipedia

How do you use methoxsalen lotion?

Dosing

  1. Adults and children 12 years of age and over—Apply to the affected area of the skin and allow to dry for one to two minutes, then apply again within two to two and one-half hours before UVA exposure.
  2. Children under 12 years of age—Use and dose must be determined by your doctor.

How do you use Octamop lotion?

Directions for Use Octamop Lotion 30 ml should be taken as prescribed by your doctor, preferably with low diet food or milk. avoid sunlight on your lips or skin for at least 8 hours after taking Octamop Lotion 30 ml. Your doctor will advise you how often you take your tablets based on your medical condition.

Where is methoxsalen from?

Natural sources. In 1947, methoxsalen was isolated (under the name “ammoidin”) from the plant Ammi majus, bishop’s weed. In 1970, Nielsen extracted 8-methoxypsoralen from four species of the genus Heracleum in the carrot family Apiaceae, including Heracleum mantegazzianum and Heracleum sphondylium.

Is methoxsalen harmful to humans?

We conclude that both methoxsalen and PUVA have toxic effects on the spermatogenesis and all spermatogenic cells.

What can I use for vitiligo?

Light therapy. Phototherapy with narrow band ultraviolet B (UVB) has been shown to stop or slow the progression of active vitiligo. It might be more effective when used with corticosteroids or calcineurin inhibitors. You’ll need therapy two to three times a week.

What is Octamop lotion?

Octamop Lotion is a medicine used along with controlled ultraviolet light for effective treatment of certain skin diseases like vitiligo and psoriasis.

How do you use Melanocyl lotion?

Diet & Lifestyle Advise

  1. Take this Melanocyl Solution 25 ml by mouth with milk or food, normally 2 to 4 hours before your UVA light treatment.
  2. Do not go into the sunlight for 24 hours before taking Melanocyl Solution 25 ml.
  3. Use extra caution for at least 48 hours after each treatment.

Is methoxsalen natural?

Methoxsalen (UVADEX) is a naturally occurring photoactive substance found in the seed of the Ammi majus plant and belongs to a class of compounds known as psoralens.

How is methoxsalen used?

Methoxsalen belongs to the group of medicines called psoralens. It is used along with ultraviolet light (found in sunlight and some special lamps) in a treatment called PUVA to treat vitiligo, a disease in which skin color is lost, and psoriasis, a skin condition associated with red and scaly patches.

What is Oxsoralen lotion made of?

Oxsoralen Lotion is a clear, colorless to straw colored liquid with an odor of acetone. Each ml. of Oxsoralen Lotion contains 10 mg. methoxsalen in an inert vehicle containing alcohol (71% v/v), propylene glycol, acetone, and purified water.

How is Oxsoralen lotion used to treat vitiligo?

Oxsoralen Lotion is applied to a well-defined area of vitiligo by the physician and the area is then exposed to a suitable source of UVA. Initial exposure time should be conservative and not exceed that which is predicted to be one-half the minimal erythema dose.

What are the warnings for methoxsalen lotion?

Oxsoralen 1 CAUTION. METHOXSALEN LOTION IS A POTENT TOPICAL DRUG. 2 Warning. METHOXSALEN LOTION IS A POTENT DRUG CAPABLE OF PRODUCING SEVERE BURNS IF IMPROPERLY USED. 3 I. DESCRIPTION. Oxsoralen Lotion is a clear, colorless to straw colored liquid with an odor… 4 II. CLINICAL PHARMACOLOGY. The exact mechanism of action of methoxsalen with…