Which are the new technologies in drug discovery?

Technology has been a major driver of advances in drug discovery. Automation, nanofluidics, imaging, software and assay technologies have played a major role in getting better data, faster.

What are the modern methods in drug discovery and development?

Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

What are the methods involved in drug discovery?

The Drug Discovery Process involves many different stages and series of actions. Typically, it can be divided into four main stages: Early Drug Discovery, Pre-Clinical Phase, Clinical Phases, and Regulatory Approval. Let’s explore the major steps that are taken in each of these stages to develop a new drug.

How has technology changed the pharmaceutical industry?

The latest technologies, like AR/VR, artificial intelligence (AI), and additive manufacturing, help pharma companies accelerate the research and development process, create personalized products, and conduct testing in innovative ways.

How does AI help in drug discovery?

A New Wave of Drug Discovery Value AI can deliver value in small-molecule drug discovery in four ways: access to new biology, improved or novel chemistry, better success rates, and quicker and cheaper discovery processes. The technology can address many challenges and constraints in traditional R&D.

What is scaffold based drug discovery?

Scaffolds. The ‘scaffold’ concept is widely applied in medicinal chemistry and drug design to generate, analyze, and compare core structures of active compounds and analog series [1]. Scaffolds might be defined algorithmically or on the basis of medicinal chemistry knowledge [1–3].

What is new drug development process?

Research for a new drug begins in the laboratory. Drugs undergo laboratory and animal testing to answer basic questions about safety. Drugs are tested on people to make sure they are safe and effective.

What is the importance of drug discovery?

Drug discovery can be described as the process of identifying chemical entities that have the potential to become therapeutic agents. A key goal of drug discovery campaigns is the recognition of new molecular entities that may be of value in the treatment of diseases that qualify as presenting unmet medical needs.

How does technology help pharmaceutical industry?

Technology can help drive faster time to market, improve quality consistency, reliability and capacity in the manufacturing process, ultimately helping guarantee an effective and efficient drug supply chain. That will clearly be the direction of travel for the pharmaceuticals industry in the years to come.