What is LNCaP cell line?

What is LNCaP cell line?

LNCaP is a cell line derived from a metastatic lymph node lesion of human prostate cancer which is androgen receptor (AR) positive, exhibits androgen-sensitive growth, and was originally reported by Horoszewicz et al. to form subcutaneous tumors in intact male athymic nude mice at a frequency of 58% [1,2].

How do you culture a LNCaP cell?

Neutralize the trypsin-EDTA by adding complete media (containing FBS) at a volume of 4x the volume of trypsin-EDTA added; centrifuge the cells and remove the supernatant. Add 6-8 mL of growth medium and gently aspirate cells with pipette. Add aliquots of cell suspension to culture vessels. incubate at 37°C in 5% CO2.

What is A549 cells?

A549 cells are lung carcinoma epithelial cells that constitute a cell line. A549 is one of the commonly used cell lines for a wide range of research applications.

What are pc3 cells?

PC-3 cells are androgen-independent human advanced adenocarcinoma cell lines with AR expression negative. Biological characteristics of these cell lines make them be widely used in the research to study pathology and genetic stability of prostate cancer. And they might contribute to the treatment of PCa.

Are A549 cells metastatic?

However, there were differences in the number of cells per HPF based on the cell type. Among NSCLC cells, A549 formed the least amount of metastatic lesions (0.9 ± 0.35 cells per HPF), while H1299, a metastatic cell line, formed the maximum number of metastatic lesions (3.6 ± 1.03 cells per HPF).

Is A549 a Nsclc?

At Labcorp we have been using A549 as a model of NSCLC for more than 10 years. We have run numerous studies in the subcutaneous setting with a number of standard agents. Above are some examples of response to paclitaxel (Figure 1) and docetaxel, bevacizumab and the combination (Figure 2).

Who is PC3?

So, now that this is covered, you must have figured out that PC3 is the reference name for the DDR3 generation of RAM. After all, DDR3 comes with improved data transfer rates and lower voltages than the previous generations. The designated number you will see beside PC3, like PC3-12800, refers to the transfer speed.

What is the survival rate of carcinoma?

Survival rates can give you an idea of what percentage of people with the same type and stage of cancer are still alive a certain amount of time (usually 5 years) after they were diagnosed….5-year relative survival rates for Merkel cell carcinoma.