What is diffusion coefficient MRI?

Apparent diffusion coefficient (ADC) is a measure of the magnitude of diffusion (of water molecules) within tissue, and is commonly clinically calculated using MRI with diffusion-weighted imaging (DWI) 1.

What is a diffusion B value?

The b-value is a factor that reflects the strength and timing of the gradients used to generate diffusion-weighted images. The higher the b-value, the stronger the diffusion effects.

What is diffusion weighted?

Diffusion weighted imaging (DWI) is a method of signal contrast generation based on the differences in Brownian motion. DWI is a method to evaluate the molecular function and micro-architecture of the human body.

What is T1 and T2 on brain MRI?

The most common MRI sequences are T1-weighted and T2-weighted scans. T1-weighted images are produced by using short TE and TR times. The contrast and brightness of the image are predominately determined by T1 properties of tissue. Conversely, T2-weighted images are produced by using longer TE and TR times.

What is ADC in prostate?

The ADC values at high diffusion gradients may be used in differentiation prostate cancer from normal prostate and prostatitis. Key Words: Diffusion-weighted MR imaging, prostate cancer, apparent diffusion coefficient (ADC), prostatitis.

Does ADC vary with B value?

A biexponential fit should be a basic requirement, considering that DWI of the human body requires restricted diffusion [26, 34–38]. In this case, the ADC value is known to vary along with b values used for calculating the ADC [26, 27].

What is T2 shine through?

T2 shine-through refers to high signal on DWI images that is not due to restricted diffusion, but rather to high T2 signal which ‘shines through’ to the DWI image. T2 shine through occurs because of long T2 decay time in some normal tissue.

What is abnormal T2 signal?

Abnormal brightness on a T2 image indicates a disease process such as trauma, infection, or cancer.

What is increased T2 signal on MRI report brain?

A hyperintensity or T2 hyperintensity is an area of high intensity on types of magnetic resonance imaging (MRI) scans of the brain of a human or of another mammal that reflect lesions produced largely by demyelination and axonal loss.

What is ADC in MRI for prostate?

Apparent diffusion coefficient (ADC) value is a quantitative measurement of DW-MRI which has shown a promising role in the detection and localization of cancer prostate [3], [10], [11], [12], [13], [14], [15], [16].