How nanotechnology is used in drug delivery?

Applying nanotechnology to drug delivery should achieve the following benefits: Improve the ability to deliver drugs that are poorly water soluble. Provide site-specific targeting to reduce drug accumulation within healthy tissue. Help retain the drug in the body long enough for effective treatment.

How are nanoparticles useful in drug delivery applications?

Due to their small size and large surface area, drug nanoparticles show increase solubility and thus enhanced bioavailability, additional ability to cross the blood brain barrier (BBB), enter the pulmonary system and be absorbed through the tight junctions of endothelial cells of the skin (Kohane, 2007).

What are the applications of nanotechnology in medicine?

Other potential applications of nanotechnology in medicine include: nanoadjuvants with immunomodulatory properties used to deliver vaccine antigens; the nano-knife, an almost non-invasive method of destroying cancer cells with high voltage electricity; and carbon nanotubes, which are already a popular way of repairing …

Which nanoparticles can be used in targeted drug delivery?

Biodegradable nanoparticles formulated from PLGA and PLA have been developed for sustained drug delivery and are especially effective for drugs with an intracellular target (Barrera et al., 1993; Davda and Labhasetwar, 2002; Panyam and Labhasetwar, 2003).

What do you think about rational use of nanotechnology in drug delivery?

Nanotechnology offers multiple benefits in treating chronic human diseases by site-specific, and target-oriented delivery of precise medicines. Recently, there are a number of outstanding applications of the nanomedicine (chemotherapeutic agents, biological agents, immunotherapeutic agents etc.)

What is nanotechnology in pharmaceutical industry?

Pharmaceutical nanotechnology is the exciting, rapidly emerging branch of medical science that deals with harnessing nanoscale materials as drug delivery and/or diagnostic tools. As drug delivery tools, nano-delivery systems can be used to enhance the site-specific, targeted delivery of precise medicines.

What is the future of nanotechnology in medicine?

There is increasing optimism that nanotechnology applied to medicine and dentistry will bring significant advances in the diagnosis, treatment, and prevention of disease. Growing interest in the future medical applications of nanotechnology is leading to the emergence of a new field called nanomedicine.

What are the disadvantages of nanoparticles in drug delivery?

Nanoparticles have the potential to cross the blood brain barrier, which makes them extremely useful as a way to deliver drugs directly to the brain. On the other hand, this is also a major drawback because nanoparticles used to carry drugs may be toxic to the brain.

What is the best drug delivery system?

Oral drug delivery is by far the most well-known and often the preferred route of drug administration due to its non-invasive nature, ease-of-use, cost-effectiveness, and the highly absorptive properties of the gastrointestinal (GI) tract.

How is nanotechnology utilized to reduce side effects during drug delivery?

Thus, they cause fewer plasma fluctuations with reduced adverse effects [23]. Being nanosized, these structures penetrate in the tissue system, facilitate easy uptake of the drug by cells, permit an efficient drug delivery, and ensure action at the targeted location.