Is DNET a cancerous tumor?
Is DNET a cancerous tumor?
A dysembryplastic neuroepithelial tumor (DNET, or DNT) is a benign (non-cancerous), slow-growing brain tumor.
What is a DNET brain tumor?
A dysembryoplastic neuroepithelial tumor (DNET) is a low-grade, slow-growing brain tumor. It is a glioneuronal tumor, which means it contains properties of both glial and neuronal cells.
How is Dnet diagnosed?
A dysembryoplastic neuroepithelial tumour is commonly diagnosed in patients who are experiencing seizures with magnetic resonance imaging (MRI), electroencephalogram (EEG). A DNT is most commonly diagnosed in children who are experiencing seizures, and when given medication do not respond to them.
What does neuroepithelial mean?
Having to do with tissue made up of sensory cells, such as tissue found in the ear, nose, and tongue.
Is a Dnet a glioma?
Most commonly found in the temporal lobe, DNTs have been classified as benign tumours. These are glioneuronal tumours comprising both glial and neuron cells and often have ties to focal cortical dysplasia….
| Dysembryoplastic neuroepithelial tumour | |
|---|---|
| DNET | |
| Specialty | Neuro-oncology, Neurosurgery |
What is a low grade glioma?
Low-grade gliomas are cancers that develop in the brain and tend to be slow growing. Although people with these tumors are only rarely cured, most are able to maintain to work, attend school, and perform other tasks for a number of years.
Are Dnet tumors hereditary?
In children, DNTs account for 0.6% of diagnosed central nervous system tumours. It has been found that males have a slightly higher risk of having these tumours. Some familial accounts of DNTs have been documented, though the genetic ties have not yet been fully confirmed.
Where do neuroepithelial cells come from?
In the adult CNS, neuroepithelial cells arise in several different areas of the brain: the subventricular zone (SVZ), the olfactory bulb and the dentate gyrus of the hippocampus. These cells do not appear in any of the peripheral nervous system.
What do neuroepithelial cells give rise to?
glial cells
The neuroepithelial cells of the neural tube give rise to two major classes of glial cells, astrocytes and oligodendrocytes, which structurally and functionally support the neurons and their axons in the CNS (Raff, 1989).
