What are the side effects of Kayexalate?

Common side effects of Kayexalate include:

  • loss of appetite,
  • upset stomach,
  • nausea,
  • vomiting,
  • constipation, or.
  • diarrhea.

What are the side effects of lactulose?

Side effects of lactulose

  • Diarrhoea. Drink lots of fluids, such as water or squash, to avoid dehydration.
  • Bloating. Take lactulose between meals instead of before or after them.
  • Wind (farting and burping)
  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Stomach pain.

When is Kayexalate contraindicated?

KAYEXALATE is contraindicated in the following conditions: patients with hypokalemia, patients with a history of hypersensitivity to polystyrene sulfonate resins, obstructive bowel disease, neonates with reduced gut motility (postoperatively or drug induced) and oral administration in neonates (see PRECAUTIONS).

Why is Kayexalate given for hyperkalemia?

Kayexalate (Sodium polystyerene sulfonate) is a cation-exchange resin that was approved in 1958 as a treatment for hyperkalemia by helping to exchange sodium for potassium in the colon and thus excreting potassium from the body. This drug has been a standard part of treatment of hyperkalemia for decades.

What are signs and symptoms of hyperkalemia?

If hyperkalemia comes on suddenly and you have very high levels of potassium, you may feel heart palpitations, shortness of breath, chest pain, nausea, or vomiting. Sudden or severe hyperkalemia is a life-threatening condition. It requires immediate medical care.

Why was Kayexalate discontinued?

However, the U.S. Food and Drug Administration (FDA) has issued a warning to avoid Kayexalate administration with sorbitol due to the risk of colonic necrosis associated with sorbitol administration.

Who should not take lactulose?

You should not use lactulose if you are on a special diet low in galactose (milk sugar). Tell your doctor if you have ever had: diabetes; or. if you need to have any type of intestinal test using a scope (such as a colonoscopy).

Can lactulose make you sick?

Lactulose may produce gaseous distention with flatulence or belching and abdominal discomfort such as cramping in about 20% of patients. Excessive dosage can lead to diarrhea with potential complications such as loss of fluids, hypokalemia, and hypernatremia. Nausea and vomiting have been reported.

What should you assess before giving Kayexalate?

Monitor serum potassium during therapy because severe hypokalemia may occur. KAYEXALATE is not totally selective for potassium, and small amounts of other cations such as magnesium and calcium can also be lost during treatment. Monitor calcium and magnesium in patients receiving KAYEXALATE.

When should Kayexalate be given?

ORAL DOSING When taken by mouth, KAYEXALATE should be taken at least 3 hours before or 3 hours after other oral medications. For patients with gastroparesis (a condition preventing your stomach from emptying properly), a 6-hour separation should be considered.