What are the applications of Raman spectroscopy?

Most common applications of Raman spectroscopy

  • Compound distribution in tablets.
  • Blend uniformity.
  • High throughput screening.
  • API concentration.
  • Powder content and purity.
  • Raw material verification.
  • Polymorphic forms.
  • Crystallinity.

What is a Raman microscope used for?

First, Raman microscopy can be used for chemical or molecular analysis of unknown compounds in a small area, down to less than a micron. Second, combined with a moving stage, Raman microscopy can map areas of a sample, useful for samples with patterns or two different regions.

What is FT Raman?

The FT-Raman spectroscopy is a specific Raman configuration designed to collect fluorescence-free and wavelength-stable measurements from a wide range of samples, spanning from crystals to biological tissues (Hirschfeld and Chase, 1986).

Which detector is used in Raman spectroscopy?

The photomultiplier tube (PMT) was commonly used as a detector for Raman spectroscopy before modern array detectors became available. PMTs are termed single-channel detectors because they have only one light sensitive area.

What is the difference between FTIR and Raman spectroscopy?

FTIR measures how much light is the remaining energy from the original light source after being passed through the substance. In comparison, Raman measures the energy that is scattered after being excited by a laser.

What are the limitations of Raman spectroscopy?

Cannot be used for metals or alloys. The Raman effect is very weak, which leads to low sensitivity, making it difficult to measure low concentrations of a substance. This can be countered by using one of the alternative techniques (e.g. Resonance Raman) which increases the effect.

What is Raman effect and what is its importance?

Raman effect is about behaviour of light in fluids. As per this concept when light travels through a fluid then there is an interaction between light and fluid which is called dispersion of light. Raman effect helps in explaining various natural phenomenon on.

How much does Raman spectrometer cost?

Commercially available Raman spectrometers cost a minimum of $12,000 U.S. and are thus unaffordable by most schools and colleges. There have been several efforts to provide cost-effective solutions for RS, and significant contributions are listed in Table 1.

What is the difference between dispersive Raman and FT-Raman?

The first is a Bruker FT-Raman Spectrometer and the second is a Renishaw Dispersive Raman Spectrometer. The difference between the two is that the Dispersive Raman uses a diffraction grating spectrometer to disperse the light scattered by the sample.

What is the difference between Raman and FTIR?

FTIR measures how much light is the remaining energy from the original light source after being passed through the substance. In comparison, Raman measures the energy that is scattered after being excited by a laser. Both identify light-colored samples.

What are the advantages of Raman spectroscopy?

Advantages of raman spectroscopy Direct scanning of sample can save time and chemical used for analysis. Real time diagnosis of material. No sample preparation required. Can be analyse sample multiple time without destruction and same can be used for other test analysis.

Why laser is used in Raman spectroscopy?

The light source used in Raman spectroscopy is a laser. The laser light is used because it is a very intense beam of nearly monochromatic light that can interact with sample molecules. When matter absorbs light, the internal energy of the matter is changed in some way.