Which two tests are the most reliable for detecting IgE antibody?

Skin tests, especially SPT, represent the most reliable and cost-effective tool for the diagnosis and management of IgE-mediated diseases,. They demonstrate a good correlation with outcomes of nasal, conjunctival, dermal, oral and bronchial challenges.

What is considered a high IgE level IU ml?

Normal mean IgE levels for the total sample were 32 IU/ml with highest levels (mean of 51 IU/ml) in school-age children. The highest IgE levels were found in patients with both asthma and eczema (mean of 985 IU/ml), followed by asthma alone (305 IU/ml), eczema alone (273 IU/ml), and allergic rhinitis (171 IU/ml).

How do you read allergy test results?

How To Interpret Results

  1. Values under 0.35 mean unlikely sensitization to the allergen.
  2. Values between 0.35-0.69 mean doubtful significance.
  3. Values between 0.70-3.49 mean there is a possibility.
  4. Values between 3.50-17.49 mean a greater possibility.
  5. Values between 17.50-49.99 mean very likely.

How accurate is the IgE blood allergy test?

A positive SPT is reliable about 50 percent of the time, but a negative SPT result is about 95 percent predictive. By itself, the positive result just indicates that your body has made allergic antibodies, called IgE, to a specific food.

What if total IgE is high?

A total IgE test result that is high means that you may have some kind of allergy. But the results of a total IgE test don’t show what you’re allergic to or how serious your allergy may be. A specific IgE test result that is high means that you may be allergic to the allergen that was tested.

What does +3 mean on an allergy test?

A test is positive if the allergen causes a wheal 3 mm greater than the negative control, and if the skin has a response to the histamine, as well. It is important to know that individuals cannot undergo skin testing if they are using antihistamines, since this blocks the histamine-mediated reaction.

What does a positive allergy test look like?

Positive results are indicated by a wheal – a raised white bump surrounded by a small circle of itchy red skin. In general, a large wheal is more likely to indicate a true food allergy, but size is not always an accurate predictor. If no wheal appears, it is unlikely that you are allergic to the test food.