Which side effect is most likely to occur with tacrolimus?

Which side effect is most likely to occur with tacrolimus?

The most common adverse reactions (≥ 40%) observed in PROGRAF-treated liver transplant patients are: tremor, headache, diarrhea, hypertension, nausea, abnormal renal function, abdominal pain, insomnia, paresthesia, anemia, pain, fever, asthenia, hyperkalemia, hypomagnesemia, and hyperglycemia.

Is tacrolimus a high risk drug?

Increased risk for developing serious infections and malignancies with tacrolimus oral capsules, oral granules, or other immunosuppressants that may lead to hospitalization or death.

Who should not take tacrolimus?

You should not use this medicine if you are allergic to tacrolimus or hydrogenated castor oil, or if you have used cyclosporine (Neoral, Sandimmune, Gengraf) within the past 24 hours. Using tacrolimus may increase your risk of developing serious infections or certain types of cancer, such as lymphoma or skin cancer.

Does tacrolimus cause memory loss?

In 100 people receiving Tacrolimus, from 4 to 20 may have: Damage to organs (heart, lungs, brain, others) which may cause changes in thinking, confusion, memory loss or shortness of breath.

Can tacrolimus cause liver damage?

The liver injury due to tacrolimus is usually mild and self-limiting and responses rapidly to dose adjustment or drug discontinuation. Other calcineurin inhibitors and immunosuppressants are generally tolerated, but rare instances of cross sensitivity to hepatic injury by cyclosporine and tacrolimus have been reported.

Does tacrolimus affect the heart?

What foods affect tacrolimus?

Does tacrolimus interact with any foods or beverages? Avoid excessive intake of high potassium foods (bananas, oranges, orange juice, potatoes, spinach, etc). Do not eat grapefruits, grapefruit juice or any soda (Fresca) or fruit juice blend that contains grapefruit juice.

Can tacrolimus affect the brain?

The neurological side effects of calcineurin inhibitors (cyclosporine and tacrolimus) are most commonly mild, such as headache, dysarthria, visual changes, and postural tremor [2]. Severe side effects can include psychosis, cortical blindness, and seizures [2].

Does tacrolimus cause brain fog?

This medicine may cause serious brain or nerve problems (eg, posterior reversible encephalopathy syndrome). Tell your doctor right away if you have blurred vision, confusion, dizziness, headache, mental changes, seizures, high blood pressure, unusual drowsiness, tiredness, or weakness, or a fast heartbeat.

Does tacrolimus affect kidney function?

Tacrolimus may decrease kidney function, usually if blood levels of tacrolimus are too high. This is why blood work is checked frequently to adjust the dosage of tacrolimus.

What is tacrolimus toxicity?

Tacrolimus toxicity commonly presents as acute renal failure. Close monitoring of serum creatinine, GFR, and urine output is necessary for patients on tacrolimus. Toxicity may also present as the development of adverse effects such as tremors, electrolyte disturbances, headaches, and increased SCr.