When would a fibrate be used for treatment?

Fibrates are clearly the drug of choice for treatment of severe hypertriglyceridemia (TG >500mg/dl) or chylomicronemia syndrome (TG >1,000mg/dl), conditions associated with an increased risk of pancreatitis.

What is the indication of fenofibrate?

Fenofibrate capsules are indicated as adjunctive therapy to diet to reduce elevated low-density lipoprotein cholesterol (LDL-C), total cholesterol (total-c), Triglycerides (TG) and apolopoprotein B (Apo B), and to increase high-density lipoprotein cholesterol (HDL-C) in adult patients with primary hypercholesterolemia …

What is the indication of bezafibrate?

Why is Bezafibrate Prescribed? (Indications) This medication is a fibrate drug, prescribed for high cholesterol in blood.

When should fibrate gemfibrozil be taken?

Gemfibrozil comes as a tablet to take by mouth. It is usually taken twice a day, 30 minutes before the morning and evening meals. Take gemfibrozil at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

How does fibrate work?

Fibrates are cholesterol-lowering medicines. They work by decreasing your triglycerides, a type of fat in your blood. Fibrates can also increase your levels of high-density lipoprotein (HDL) cholesterol. If you have high triglycerides, taking fibrates may decrease your risk of heart disease, heart attack and stroke.

When should fenofibrate be prescribed?

Fenofibrate is used to improve cholesterol levels in three types of cholesterol problems: Mixed dyslipidemia: high levels of LDL (bad) cholesterol and triglycerides, and low levels of HDL (good) cholesterol. Severe hypertriglyceridemia: very high levels of triglycerides.

What are the side effects of bezafibrate?

Side effects of Bezafibrate include:

  • Stomach upset.
  • Stomach pain.
  • Gas.
  • Nausea.
  • Itchy skin.
  • Redness.
  • Headache.
  • Dizziness.

What drug class is bezafibrate?

Bezafibrate belongs to the class of medications known as fibrates. Bezafibrate is used in addition to diet and other measures to treat high cholesterol and high-to-very-high levels of triglycerides, a type of lipid (fat).

What are the contraindications of gemfibrozil?

Contraindications for using gemfibrozil include hepatic or severe renal dysfunction (including primary biliary cirrhosis), presence of cholelithiasis, gallbladder abnormalities, hypersensitivity, and combination therapy of gemfibrozil with the following drugs: simvastatin, repaglinide, or dasabuvir.