What was so significant about Salvarsan 606?
What was so significant about Salvarsan 606?
importance to medical technology …made, but better known as Salvarsan—which was effective against syphilis. The significance of this discovery, made in 1910, was that 606 was the first drug devised to overwhelm an invading microorganism without offending the host.
What is arsphenamine used to treat?
Arsphenamine was used to treat the disease syphilis because it is toxic to the bacterium Treponema pallidum, a spirochete that causes syphilis.
Is arsphenamine used today?
Uses. In the past, arsenic compounds have been used as medicines, including arsphenamine and neosalvasan which were indicated for syphilis and trypanosomiasis but have now been supplanted by modern antibiotics.
What did Salvarsan treat?
Salvarsan was used to treat syphilis until the 1940s. In the 19th century arsenic was often the poison of choice for murderers. In the early 20th century its image was redeemed when an arsenic derivative became the salvation of those suffering from syphilis.
What is neo Arsphenamine?
Medical Definition of neoarsphenamine : a yellow powder C13H13As2N2NaO4S similar to arsphenamine in structure and use. — called also neosalvarsan.
Is Salvarsan toxic to humans?
Salvarsan was the first effective treatment discovered for syphilis. Although salvarsan is toxic to human beings, its effect on the bacteria, spirochete, which causes syphilis is much greater than on human beings.
What is neo arsphenamine?
What is arsphenamine made of?
Arsphenamine (salvarsan) is a mixture of a trivalent triphenyl and a pentavalent pentaphenyl organoarsenic compounds. Neosalvarsan (pharmaceutical historically used for treating syphilis).
What is Arsphenamine made of?
Who found arsphenamine?
One of the first chemotherapeutic agents, salvarsan (arsphenamine), was discovered in 1908 by Paul Ehrlich (as his 606th arsenic compound tested). Salvarsan was used to treat syphilis and trypanosomiasis until penicillin was introduced (1945).
