What typically brings on clinical depression?

There’s no single cause of depression. It can occur for a variety of reasons and it has many different triggers. For some people, an upsetting or stressful life event, such as bereavement, divorce, illness, redundancy and job or money worries, can be the cause. Different causes can often combine to trigger depression.

What are the biomarkers for depression?

Polymorphisms in genes associated with serotonin transporter, serotonin 2A receptor, monoamine oxidase (MAO)A, BDNF, tryptophan hydroxylase, and GRs have been investigated as potential biomarkers in depression (115–117).

What are 5 main areas of functioning may be affected when someone is experiencing depression?

Loss of energy, insomnia, concentration difficulties and thoughts of death appeared in all countries, whereas weight loss, increased appetite, hypersomnia, retardation, agitation and decrease in sexual interest were determined as country-specific (Weissman et al., 1996).

Can you heal from clinical depression?

Major or clinical depression is a serious but treatable illness. Depending on the severity of symptoms, your primary care doctor or a psychiatrist may recommend treatment with an antidepressant medication. They may also suggest psychotherapy, or talk therapy, in which you address your emotional state.

Whats the difference between depression and clinical depression?

Depression ranges in seriousness from mild, temporary episodes of sadness to severe, persistent depression. Clinical depression is the more-severe form of depression, also known as major depression or major depressive disorder.

What causes clinical depression in the brain?

Research suggests that depression doesn’t spring from simply having too much or too little of certain brain chemicals. Rather, there are many possible causes of depression, including faulty mood regulation by the brain, genetic vulnerability, and stressful life events.

What are the most reliable biological depression markers?

Cortisol is the most common HPA axis biomarker to have been studied in depression.

Who is most likely to suffer from depression?

Age. Major depression is most likely to affect people between the ages of 45 and 65. “People in middle age are at the top of the bell curve for depression, but the people at each end of the curve, the very young and very old, may be at higher risk for severe depression,” says Walch.