What type of nanoparticle is Abraxane?

Abraxane is a 130 nm albumin-bound particle form of paclitaxel (PTX), which is a member of the taxane family and an important agent in cancer chemotherapy.

Is Abraxane a nanoparticle?

To date, paclitaxel albumin-bound nanoparticles (Abraxane®) have been approved by the FDA for the treatment of metastatic breast cancer and non-small cell lung cancer (NSCLC). In addition, there are a number of novel paclitaxel nanoparticle formulations in clinical trials.

What is Nano paclitaxel?

(NA-noh-PAR-tih-kul PA-klih-TAK-sil) A form of the anticancer drug paclitaxel that is used alone or with other drugs to treat certain types of breast cancer, non-small cell lung cancer, and pancreatic cancer. Nanoparticle paclitaxel may have fewer side effects and work better than other forms of paclitaxel.

What is Abraxane made of?

Abraxane is made from donated human plasma and may contain viruses or other infectious agents. Donated plasma is tested and treated to reduce the risk of contamination, but there is still a small possibility it could transmit disease. Ask your doctor about any possible risk.

Why is Abraxane protein bound?

About: Paclitaxel, Protein Bound (Abraxane®) This prevents the reactions associated with the preservative used in regular paclitaxel and allows higher doses to be given.

How is Abraxane different than Taxol?

Abraxane is a different form of paclitaxel than Taxol. Both medicines are taxanes, a powerful type of chemotherapy that can stop cancer cells from repairing themselves and making new cells. Taxol uses a solvent called Cremophor EL to dissolve its main ingredients so the medicine can enter the bloodstream.

Why is ABRAXANE protein bound?

How is ABRAXANE different than Taxol?

What is the difference between Abraxane and paclitaxel?

Abraxane is a new form of paclitaxel that is bound with albumin, a type of protein normally found in the human body. This form of paclitaxel delivers high concentrations of the active ingredient into the cancer cells and, compared to the original form of the drug, reduces the incidence of side effects.

Is paclitaxel a nanoparticle?

Paclitaxel albumin-stabilized nanoparticle formulation is a form of paclitaxel contained in nanoparticles (very tiny particles of protein). The drug is also called nanoparticle paclitaxel and protein-bound paclitaxel.

What type of drug is Abraxane?

Nab-paclitaxel is a chemotherapy drug and is also known by its brand name, Abraxane. It combines the chemotherapy drug paclitaxel with a protein called albumin. It is a treatment for: breast cancer that has spread.

What is paclitaxel protein bound particles?

Paclitaxel, protein bound, is a form of paclitaxel chemotherapy where the paclitaxel particles are bound in a protein called albumin, which is derived from human blood. This prevents the reactions associated with the preservative used in regular paclitaxel and allows higher doses to be given.