What routes can nitroglycerin be given?

Nitroglycerin (Oral Route, Sublingual Route)

Which of the following administration routes for nitroglycerin is the most common?

Sublingual administration, in which a tablet or troche is allowed to dissolve completely in the oral cavity, takes advantage of the permeability of the oral epithelium and is the preferred route for a few potent lipophilic drugs, such as nitroglycerin and oxytocin, and even the commonly used oral sedative triazolam.

How do you administer nitroglycerin injection?

Initially, 0.25 to 0.5 mcg/kg/minute continuous IV infusion. Titrate by 1 mcg/kg/minute IV every 15 to 20 minutes as tolerated. The usual dosage range is 1 to 5 mcg/kg/minute. Usual Max: 10 mcg/kg/minute ; however, rates up to 20 mcg/kg/minute have been used.

Which route of administration is recommended for nitrostat?

NITROSTAT is indicated for the acute relief of an attack or acute prophylaxis of angina pectoris due to coronary artery disease. Administer one tablet under the tongue or in the buccal pouch at the first sign of an acute anginal attack.

What is the appropriate route for nitroglycerin administration by the EMT?

To administer a sublingual (SL) medication, place the pill or direct the spray between the underside of the tongue and the floor of the oral cavity. The medication is rapidly absorbed through the mucous membranes of the mouth and blood vessels of the tongue. The most common drug given by this route is nitroglycerin.

Can nitroglycerin be given intravenously?

Nitroglycerin (Intravenous Route)

What IV tubing is used for nitroglycerin?

Abstract. Nitroglycerin is absorbed in vitro into polyvinyl chloride tubing, and it has been recommended that nitroglycerin be administered intravenously through specialized polyethylene infusion sets.

Why nitroglycerin is given sublingually?

Glyceryl trinitrate (or nitroglycerin) undergoes extensive hepatic presystemic metabolism when given orally, and is therefore usually given by the sublingual route, by which it is well absorbed and rapidly taken up into the circulation.

How is nitroglycerin usually given by the EMT?

There are intravenous (IV) routes of administration for nitroglycerin used most commonly in emergency rooms and intensive care units (ICU).

What are the five rights of medication administration?

One of the recommendations to reduce medication errors and harm is to use the “five rights”: the right patient, the right drug, the right dose, the right route, and the right time.

When is nitroglycerin not administered?

The contraindications of nitroglycerine therapy include:

  1. Allergic reactions to nitroglycerin are extremely rare, but reports do exist.
  2. Known history of increased intracranial pressure, severe anemia, right-sided myocardial infarction, or hypersensitivity to nitroglycerin are contraindications to nitroglycerin therapy.

https://www.youtube.com/watch?v=ryFqEyNcim0