What is ulcerative Proctosigmoiditis?

Ulcerative proctosigmoiditis is one of the four types of ulcerative colitis. Proctosigmoiditis causes inflammation in your colon and rectum. This type is different from ulcerative proctitis, which is confined to your rectum.‌

What is indeterminate IBD?

Indeterminate colitis (IC) originally referred to those 10-15% of cases of inflammatory bowel disease (IBD) in which there was difficulty distinguishing between ulcerative colitis (UC) and Crohn’s disease (CD) in the colectomy specimen.

Is mesalamine the same as mesalazine?

Oral mesalazine (also known as mesalamine) is a 5-aminosalicylic acid compound used in the treatment of mild to moderate ulcerative colitis, with high rates of efficacy in induction and maintenance of remission. The therapeutic effect of mesalazine occurs topically at the site of diseased colonic mucosa.

What is IC IBD?

Background: Indeterminate colitis (IC) is a subgroup of inflammatory bowel disease (IBD) that cannot be characterized as either ulcerative colitis (UC) or Crohn’s disease (CD).

How is indeterminate colitis diagnosed?

The serologic markers that have proven most useful for diagnosing indeterminate colitis are anti—Saccharomyces cerevisiae antibody (ASCA) and perinuclear antineutrophil cytoplasmic antibody (pANCA), also known as nuclear-specific antigen. Most patients with indeterminate colitis are negative for both of these markers.

How is indeterminate colitis treated?

The treatment options for indeterminate colitis are similar to IBD and include, but are not limited to:

  1. Biologic therapy.
  2. Corticosteroids.
  3. Anti-inflammatory medications.
  4. Immune system-suppressing medications.
  5. Antibiotics.
  6. Surgery (in some cases) 1,2

Can you take mesalamine long term?

Mesalazine can be taken long term. However your doctor will want to check how your kidneys are working during treatment. In rare cases mesalazine can cause kidney problems. These checks usually happen once every 3 months for the first year.

What is the difference between Crohn’s disease and ulcerative colitis?

In Crohn’s disease, there are healthy parts of the intestine mixed in between inflamed areas. Ulcerative colitis, on the other hand, is continuous inflammation of the colon. Ulcerative colitis only affects the inner most lining of the colon while Crohn’s disease can occur in all the layers of the bowel walls.

What is Montreal classification?

With respect to age of onset, the Montreal classification allows for early onset of disease to be categorised separately as a new A1 category for those with age of diagnosis at 16 years or younger, whereas A2 and A3 account for age of diagnosis at 17–40 years and >40 years, respectively (table 1​).