What is the most common cause of SIADH?

The most common causes of SIADH are malignancy, pulmonary disorders, CNS disorders and medication; these are summarised in Table 3. SIADH was originally described by Bartter & Schwartz in two patients with lung carcinoma, who had severe hyponatraemia at presentation (29).

Which disease is associated with SIADH?

Chronic hyponatremia is associated with nervous system problems such as poor balance and poor memory. Many causes of SIADH are reversible. Rapid correction of chronic hyponatremia can also cause dangerous complications (osmotic demyelination).

What is the best treatment for SIADH?

The most commonly prescribed treatment for SIADH is fluid and water restriction. If the condition is chronic, fluid restriction may need to be permanent. Treatment may also include: Certain medications that inhibit the action of ADH (also called vasopressin)

How do you get SIADH?

SIADH is a syndrome of inappropriate antidiuretic hormone secretion. Things that cause SIADH include infections, asthma, brain inflammation, certain medications, hereditary factors and other factors.

What are the complications of SIADH?

Complications of SIADH depend on how low blood sodium levels are….Complications

  • Headaches.
  • Depression.
  • Memory problems.
  • Muscle cramps.
  • Tremors.

Do you urinate a lot with SIADH?

The side effects are thirst, polydipsia and frequency of urination. In any therapy of chronic SIADH it is important to limit the daily increase of serum sodium to less than 8–10 mmol/liter because higher correction rates have been associated with osmotic demyelination.

How serious is SIADH?

It lowers the amount of urine the body makes and increases the amount of water the kidneys take up. Too much ADH leads to water retention, electrolyte imbalances and a low level of sodium in the blood (called hyponatremia or water intoxication). SIADH that develops suddenly can be life-threatening.

Is SIADH life threatening?

What is the most serious complication of SIADH?

A low sodium level or hyponatremia is a major complication of SIADH and is responsible for many of the symptoms of SIADH.

What cancers can cause SIADH?

Approximately 67% of SIADH cases are reported to be caused by cancer, the majority of which (70%) are linked to small cell carcinoma of the lung (1). Head and neck cancers are responsible for only 1.5% of SIADH cases; however, the majority of these cases have the histology of small cell carcinoma (2).

Which of the following is a serious complication of SIADH?

A low sodium level or hyponatremia is a major complication of SIADH and is responsible for many of the symptoms of SIADH. Early symptoms may be mild and include cramping, nausea, and vomiting. In severe cases, SIADH can cause confusion, seizures, and coma.