What is the main cause of DIC?

The underlying cause is usually due to inflammation, infection, or cancer. In some cases of DIC, small blood clots form in the blood vessels. Some of these clots can clog the vessels and cut off the normal blood supply to organs such as the liver, brain, or kidneys.

What causes DIC in pregnancy?

Acute obstetrical hemorrhage is one of the leading causes for DIC in pregnancy and is one of the most avoidable etiologies of maternal death.

Why is heparin used in DIC?

Heparin, as an anticoagulant, which, not only inhibits the activation of the coagulation system, but is also an anti-inflammatory and immunomodulatory agent, has been widely used during DIC treatment and in the prevention and treatment of thrombotic diseases.

What bacteria causes DIC?

DIC is classically associated with Gram negative bacterial infections but it can occur with a similar incidence in Gram positive sepsis. Moreover, systemic infections with other micro-organisms, such as viruses, Rickettsiae and even parasites (e.g. Plasmodium falciparum) may also result in DIC.

How does DIC cause death?

Disseminated intravascular coagulation (DIC) is a rare, life threatening condition. It’s also sometimes called consumption coagulopathy. In the early stages of the condition, DIC causes your blood to clot excessively. As a result, blood clots may reduce blood flow and block blood from reaching bodily organs.

How does DIC lead to death?

Can cesarean cause DIC?

A typical case of DIC presumably precipitated by cesarean section done for severe toxemia of pregnancy is reported. A laboratory study followed up the progress of DIC, especially of the drop in the consumptive platelet count and fibrinogen level as a result of excessive blood clotting.

Why DIC occurs in missed abortion?

The most common cause of abortion-related DIC is amniotic fluid embolism, which is when amniotic fluid gets into the mother’s blood stream. This can be caused by lacerations of the uterus or by compromised blood vessels when the placenta detaches.