What is the main apoprotein present in HDL?

The major apolipoproteins of HDL are apo A-I and apo A-II, the alpha lipoproteins. An elevated concentration of apo A-I and apo A-II, known as hyperalphalipoproteinemia (HALP), is associated with a lower risk of CHD.

Which apolipoprotein is found only in HDL?

Apolipoprotein A-II Apo A-II is synthesized in the liver and is the second most abundant protein on HDL accounting for approximately 20% of HDL protein. The role of Apo A-II in lipid metabolism is unclear. Apo A-II is a strong predictor of risk for CVD.

What food sources are high in HDL?

However, there’s also a “good” type of cholesterol that your body needs. This is called high-density lipoprotein (HDL) cholesterol….Fatty fish

  • salmon.
  • mackerel.
  • albacore tuna.
  • sardines.
  • rainbow trout.

What is the main apoprotein present on LDL?

Low-Density Lipoproteins LDL is the major cholesterol-carrying particle in the plasma. The core is cholesterol ester and has one apolipoprotein, apoB-100, per LDL particle.

Which Apoprotein is inversely related to risk of coronary heart disease?

Also, after adjustment for high-density lipoprotein particle number and size, apoA-II was still associated with the risk of future CAD (odds ratio 0.62, 95% confidence interval 0.43 to 0.90, P for linearity 0.02). Conclusions— ApoA-II is associated with a decreased risk of future CAD in apparently healthy people.

What does high apolipoprotein B mean?

Normal levels of ApoB-100 in adults are less than 100 mg/dL. Your risk is high if you have a result greater than 110 mg/dL. High levels of ApoB may mean that you have a higher than normal risk of developing cardiovascular disease. An ApoA test (linked with “good” cholesterol) may also be done with the ApoB test.

How does LDL differ from HDL?

As a general rule, HDL is considered “good” cholesterol, while LDL is considered “bad.” This is because HDL carries cholesterol to your liver, where it can be removed from your bloodstream before it builds up in your arteries. LDL, on the other hand, takes cholesterol directly to your arteries.

What does Apoprotein C do?

The main role of apoC-II secreted by the liver into the plasma is to enhance TG hydrolysis of VLDL and CM for energy delivery or storage. Consequently, the APOC2 gene in the liver responds to metabolic cues by activation of transcription factors and nuclear hormone receptors.