What is the drug of choice for C. diff?

Antibiotics are the mainstay to treat C. difficile infection. Commonly used antibiotics include: Vancomycin (Vancocin HCL, Firvanq)

What is the ICD-10 for C. diff colitis?

ICD-10 code A04. 7 for Enterocolitis due to Clostridium difficile is a medical classification as listed by WHO under the range – Certain infectious and parasitic diseases .

What is the first line drug for C. diff?

Fidaxomicin as First Line Very simply and clearly, fidaxomicin is now recommended as the preferred agent for Clostridioides difficile infection (CDI) over vancomycin.

What is the recommended treatment for Clostridium difficile colitis?

Antibiotic treatment is recommended for all except very mild cases actually triggered by antibiotic use; suitable treatments include metronidazole, vancomycin, and fidaxomicin. For mild/moderate disease, oral metronidazole (500 mg 3 times daily for 10 days) is recommended as the initial treatment.

What treatment is most effective for C. difficile infections?

Treatment of primary infection caused by C. difficile is an antibiotic such as metronidazole, vancomycin, or fidaxomicin. While metronidazole is not approved for treating C. difficile infections by the FDA, it has been commonly recommended and used for mild C.

Is fidaxomicin a penicillin?

Fidaxomicin is in a class of medications called macrolide antibiotics. It works by killing bacteria in the intestines.

What type of bacteria is C. diff?

C. diff is a spore-forming, Gram-positive anaerobic bacillus that produces two exotoxins: toxin A and toxin B. It is a common cause of antibiotic-associated diarrhea (AAD) and accounts for 15 to 25% of all episodes of AAD.

What is the most common treatment for C diff?

Commonly prescribed medications include metronidazole, vancomycin, and fidaxomicin. Your doctor chooses the antibiotic based on the severity of your symptoms. For people with a mild-to-moderate C. difficile infection, a doctor may prescribe metronidazole.

Which is better vancomycin or fidaxomicin?

According to the study, fidaxomicin was evaluated in almost 900 patients in six randomized controlled trials. In achieving a sustained cure, the researchers found that fidaxomicin was significantly better than vancomycin, metronidazole, bacitracin and tolevamer.

Is vancomycin the same as Flagyl?

Metronidazole and vancomycin are antibiotics used to treat Clostridium difficile diarrhea. Brand names for metronidazole include Flagyl and Flagyl ER and a brand name for vancomycin is Vancocin HCL.