What is the difference between Prolastin and Prolastin-C?
What is the difference between Prolastin and Prolastin-C?
What is the difference between PROLASTIN-C and PROLASTIN-C LIQUID? PROLASTIN-C LIQUID is the same medicine you have been receiving in a lyophilized (powder) formulation, but is now available in a convenient, ready-to-infuse liquid formulation.
Who manufactures Prolastin-C?
About Grifols: Manufacturer of PROLASTIN-C Liquid.
What are the side effects of Prolastin?
What Are Side Effects of Prolastin?
- pain at the injection site.
- fever.
- dizziness.
- headache.
- drowsiness.
- numb/tingling skin.
- muscle aches or pain.
- nausea.
What is Prolastin-C liquid?
PROLASTIN-C LIQUID is an alpha1-proteinase inhibitor (human) (alpha1-PI) indicated for chronic augmentation and maintenance therapy in adults with clinical evidence of emphysema due to severe hereditary deficiency of alpha1-PI (alpha1-antitrypsin deficiency).
How much does Prolastin C cost?
Prolastin-C is a Alpha-Proteinase Inhibitor (Human) class medicine made by Grifols Usa. The average retail price for Prolastin-C is $16,158.72 per 25248, 1000MG/20ML Solution.
Is Prolastin covered by Medicare?
Do Medicare prescription drug plans cover Prolastin C? Yes. 96% of Medicare prescription drug plans cover this drug.
How much does Prolastin-C cost?
How is Prolastin-C made?
Because PROLASTIN-C LIQUID is made from human plasma, it may carry a risk of transmitting infectious agents, eg, viruses, the variant Creutzfeldt-Jakob disease (vCJD) agent, and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent. This also applies to unknown or emerging viruses and other pathogens.
How often is Prolastin given?
Dose. The recommended dose of PROLASTIN-C LIQUID is 60 mg/kg body weight administered intravenously once weekly.
How does Prolastin-C work?
Prolastin-C is a protein (alpha 1-antitrypsin) that occurs naturally in the body and helps prevent breakdown of tissues in the lungs. People who lack this protein because of a genetic deficiency can develop damage to the air sacs in the lungs (emphysema).
How is Prolastin-C administered?
PROLASTIN-C LIQUID should be given intravenously at a rate 0.08 mL/kg/min as determined by the response and comfort of the patient.
Is Prolastin C covered by Medicare?
Yes. 96% of Medicare prescription drug plans cover this drug.
What is the difference between Prolastin-C liquid and Prolastin?
Using the functional activity assay, Prolastin-C resulted in a mean trough of 11.8 ± 2.2 µM and PROLASTIN resulted in a mean trough of 11.0 ± 2.2 µM. Carcinogenesis, mutagenesis, and impairment of fertility studies were not performed; Prolastin-C LIQUID is a biologic purified from human plasma.
What are the possible side effects of Prolastin?
The following adverse reactions have been identified and reported during the post marketing use of the predecessor product, PROLASTIN: 1 Respiratory: dyspnea. 2 Cardiac: tachycardia. 3 Skin and Subcutaneous: rash. 4 General/Body as a Whole: chest pain, chills, influenza-like illness. 5 Immune: hypersensitivity. 6 (more items)
How many milligrams of Prolastin C are in a vial?
Dosage Forms and Strengths Prolastin-C LIQUID is a solution for injection containing approximately 500 mg (10 mL), 1,000 mg (20 mL), and 4,000 mg (80 mL) in single-dose vials. The actual amount of functionally active Alpha 1 -PI in milligrams is printed on the vial label and carton.
Is Prolastin C contraindicated in IgA deficient patients?
Prolastin-C is supplied in 1000 mg single use vials with a separate 20 mL vial of Sterile Water for Injection, USP. Prolastin-C is contraindicated in IgA deficient patients with antibodies against IgA, due to the risk of severe hypersensitivity.
