What is the Crevicular fluid?

Gingival crevicular fluid (GCF) is an inflammatory exudate derived from the periodontal tissues. It is composed of serum and locally generated materials such as tissue breakdown products, inflammatory mediators, and antibodies directed against dental plaque bacteria.

What is Sulcular fluid?

fluid containing plasma proteins, which is present in increasing amounts in association with gingival inflammation.

Which fluid is both exudate and transudate in oral cavity?

Gingival crevicular fluid (GCF), a serum transudate or inflammatory exudate, can be collected from the gingival crevice surrounding the teeth. As such, the fluid reflects the constituents of serum, the cellular response in the periodontium, and contributions from the gingival crevice.

Which immunoglobulin is concentrated in gingival crevicular fluid?

Background: In previous studies, we demonstrated that increased levels of immunoglobulin A (IgA) in gingival crevicular fluid (GCF) may be “protective”, while increased levels of the polymorphonuclear lysosomal enzyme, beta-glucuronidase, in GCF were associated with increased risk of disease activity.

Is GCF an exudate or transudate?

Originally, most investigators classified GCF as an inflammatory exudate (18). However, there is evidence to suggest that GCF from clinically normal tissue is an altered serum transudate that only becomes an inflammatory exudate when disease is clinically present (76).

How do you collect gingival crevicular fluid?

Furthermore, paper strips are the most convenient and accurate method for gingival crevicular fluid collection, while enzyme-linked immunosorbent assay can be considered the most conventional method for the diagnosis of biofluids.

Is GCF transudate or exudate?

What is sulcular epithelium?

The sulcular epithelium is that epithelium which lines the gingival sulcus. It is apically bounded by the junctional epithelium and meets the epithelium of the oral cavity at the height of the free gingival margin. The sulcular epithelium is nonkeratinized.

What immunoglobulin is in saliva?

Secretory immunoglobulin A (SIgA)
Secretory immunoglobulin A (SIgA) constitutes the predominant immunoglobulin isotype in secretions, including saliva. It is considered to be the first line of defense of the host against pathogens which colonize or invade surfaces bathed by external secretions (320, 328).

What is transudate edema?

A transudate is a filtrate of blood. It is due to increased pressure in the veins and capillaries that forces fluid through the vessel walls or to a low level of protein in blood serum. Transudate accumulates in tissues outside the blood vessels and causes edema (swelling).

What bacteria causes acute necrotizing ulcerative gingivitis?

Acute necrotizing ulcerative gingivitis, otherwise known as Vincent’s angina or trench mouth, is caused by an imbalance in the normal flora of the gingival sulcus with predominant presence of the spirochete Borrelia vincentii and the gram-negative bacillus Fusiformis fusiform.