What is the CrCl equation?

The Cockcroft-Gault formula for estimating creatinine clearance (CrCl) should be used routinely as a simple means to provide a reliable approximation of residual renal function in all patients with CKD. The formulas are as follows: CrCl (male) = ([140-age] × weight in kg)/(serum creatinine × 72)

What is the reference range for creatinine clearance for females?

Clearance is often measured as milliliters per minute (mL/min) or milliliters per second (mL/s). Normal values are: Male: 97 to 137 mL/min (1.65 to 2.33 mL/s). Female: 88 to 128 mL/min (1.496 to 2.18 mL/s).

How is CrCl calculated example?

  1. Now we can use Cockcroft-Gault equation to calculate creatinine clearance: CrCl = (140 – age) * weight * sex / (72 * sCr) CrCl = (140 – 67) * 78.14 * 1 / (72 * 1.4) CrCl = 73 * 78.14 * 1 / 100.8. CrCl = 5704.22 / 100.8.
  2. Looking at this result, we can assume that patient’s CrCl is below the normal range.

How is CrCl calculated for obese?

Background

  1. Program is based on the following: Estimating Creatinine Clearance (ml/min)
  2. For Men: [137 – age] x [(0.285 x weight(kg)) + (12.1 x height(m)2)] ———————————————————–
  3. For Women: [146 – age] x [(0.287 x weight(kg)) + (9.74 x height(m)2)]
  4. Units: Weight: kg Height: meters.

How is CrCl calculated in Aki?

  1. CockcroftGault. CrCl (mL/min) = (140 − age (years) x weight (kg) x 0.85 [female])/(SCr (mg/dL) x 72)
  2. MDRD (four-variable) study equation. GFR (mL/min per 1.73m2) = 186.3 x SCr-1.154 x age-0.203 x 1.212 [African American] x 0.742 [female]
  3. MDRD (four-variable) study equation using IDMS SCr.
  4. CKD-EPIa.

What weight should I use for CrCl?

Cockcroft and Gault equation utilizing the ibw (Ideal body weight) to calculate an estimated creatinine clearance. actual body weight for calculating the CRCL. Males: IBW = 50 kg + 2.3 kg for each inch over 5 feet. Females: IBW = 45.5 kg + 2.3 kg for each inch over 5 feet.

How is CrCl calculated in elderly?

Specifically, GFR can be estimated by calculating creatinine clearance (CrCl) using the Cockcroft-Gault equation, which uses a patient’s age in years, body weight in kg, serum creatinine level in mg/dL, and sex to estimate the CrCl: ([140 – age] × body weight / 72 × serum creatinine) × 0.85 (if female).

What is normal creatinine clearance for age?

Creatinine clearance rates go down as you age. For every decade after age 40, a normal test result is 6.5 mL/min less than the numbers above. For newborns, the normal range is 40 to 65 mL/min. An abnormal creatinine clearance rate may mean you have a problem with your kidneys.

Can you calculate CrCl without weight?

Where creatinine clearance is calculated to determine DOAC dose this should be done using the Cockcroft and Gault formula and ACTUAL body weight 1. Ideal body weight should not be used for this purpose as it can result in inappropriate dose reductions and an increased risk of stroke/systemic embolus.

Can you calculate CrCl without height?

If no height is provided, you can only use TBW because you cannot calculate IBW without height.

What weight do you use for CrCl?

When should I use ideal weight for creatinine clearance?

CrCL e CG routine practice: Estimated CrCL using the Cockcroft-Gault equation in which ideal body weight is routine, actual body weight is utilized if a patient weighs less than his/her ideal body weight, and adjusted body weight used when patient,s actual body weight is greater than 130% of ideal body weight.