What is the chemical name of clonazepam?
What is the chemical name of clonazepam?
Clonazepam
| Clinical data | |
|---|---|
| Identifiers | |
| IUPAC name 5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-1,4-benzodiazepin-2-one | |
| CAS Number | 1622-61-3 |
| PubChem CID | 2802 |
What are the active metabolites of clonazepam?
Clonazepam is detected as the metabolite 7-aminoclonazepam. Flunitrazepam is detected as the metabolite 7-aminoflunitrazepam. Flurazepam is detected as the metabolite hydroxyethyl-flurazepam.
How does clonazepam work in the brain?
Clonazepam belongs to a group of medicines called benzodiazepines. It works by increasing levels of a calming chemical, gamma-amino-butyric-acid (GABA), in your brain. Depending on your health condition, this can relieve anxiety, stop seizures and fits or relax tense muscles.
What is the mechanism of action of clonazepam?
Mechanism of Action Clonazepam is highly potent and a long-acting benzodiazepine. It exerts pharmacological effects by acting as a positive allosteric modulator on GABA-A receptors. The GABA-A receptor is a ligand-gated chloride ion-selective channel which endogenous ligand is GABA (gamma-aminobutyric acid).
What is clonazepam generic for?
Clonazepam is a generic drug. It’s also sold as the brand-name drug Klonopin. Xanax, on the other hand, is a brand-name version of the drug alprazolam. Both clonazepam and Xanax are central nervous system (CNS) depressants and are classified as benzodiazepines.
What is clonazepam made out of?
containing 0.5 mg of clonazepam and unscored tablets with a K-shaped perforation containing 1 mg or 2 mg of clonazepam. Each tablet also contains lactose, magnesium stearate, microcrystalline cellulose and corn starch, with the following colorants: 0.5 mg—FD&C Yellow No.
What does Clonazolam metabolized into?
Data revealed that clonazolam and meclonazepam were extensively metabolized and mainly excreted as their amino and acetamino metabolites.
Does clonazepam increase dopamine?
These study results suggest that clonazepam contributed to the improvement of dopamine sensitivity.
What neurotransmitters affect Klonopin?
While the exact mechanism of action of Klonopin is not known, it is thought that it works by enhancing the effects of an inhibitory neurotransmitter called gamma-aminobutyric acid (GABA). GABA works to reduce the excitability of neurons. In effect, GABA “tunes down” signals emitted by nerve cells.
What drug is similar to clonazepam?
Alprazolam (Xanax) and clonazepam (Klonopin) are both medications that affect a person’s central nervous system (CNS) by slowing it down. They belong to a family of drugs called benzodiazepines. Doctors tend to prescribe these to treat anxiety and panic disorders.
