What is the cause of early primary tooth loss in patients with Papillon Lefevre syndrome?

Papillon–Lefèvre syndrome (PLS) is a rare autosomal recessive disorder, characterized by diffuse palmoplantar keratoderma and precocious aggressive periodontitis, leading to premature loss of deciduous and permanent dentition at a very young age.

Is Papillon Lefevre syndrome genetic?

Papillon–Lefèvre syndrome (PLS), also known as palmoplantar keratoderma with periodontitis, is an autosomal recessive genetic disorder caused by a deficiency in cathepsin C. Papillon–Lefèvre syndrome has an autosomal recessive pattern of inheritance.

What is aggressive periodontitis?

Aggressive periodontitis is a destructive disease characterized by the following: the involvement of multiple teeth with a distinctive pattern of periodontal tissue loss; a high rate of disease progression; an early age of onset; and the absence of systemic diseases.

What is trenchmouth?

Trench mouth is an infection that causes swelling (inflammation) and ulcers in the gums (gingivae). The term trench mouth comes from World War I, when this infection was common among soldiers “in the trenches.” The appearance of normal teeth varies, especially the molars.

How do you pronounce Papillon Lefevre?

papillon-lefevre disease Pronunciation. pa·pil·lon-lefevre dis·ease.

How is juvenile periodontitis treated?

If the disease process is observed at a very early stage, treatment can include subgingival scaling and root planing in conjunction with antibiotic therapy. The bacteria associated with this disease process are particularly susceptible to antibiotics such as tetracycline or doxycycline.

Is juvenile periodontitis and aggressive periodontitis same?

In general, the new term “localized aggressive periodontitis” replaces what was previously known as “localized juvenile periodontitis.” Similarly, “generalized aggressive periodontitis” replaces what used to be called “generalized juvenile periodontitis.” Aggressive periodontitis is a specific type of periodontitis …

Can periodontal disease make you feel sick?

Fever, Chills, Bleeding Gums: Potential Periodontal Disease. As we mentioned when discussing dental abscesses, oral infections can present with flu-like symptoms. This holds true when you experience periodontal disease, also called gum disease.

What is rapidly progressive periodontitis?

Rapidly progression periodontitis or aggressive periodontitis causes rapid destruction of the periodontium which leads to early tooth loss. It may be generalized or localized.