What is the best triple therapy for H. pylori?

RECOMMENDED. Clarithromycin triple therapy consists of a PPI, clarithromycin (Biaxin), and amoxicillin or metronidazole (Flagyl) for 14 days. The effect of H. pylori resistance to clarithromycin is well documented.

What is standard triple therapy for H. pylori?

Helicobacter pylori (Hp) infection is the most common bacterial infection in the world. The most recommended treatment for the eradication of Hp is the standard triple therapy (STT) consisting of a proton pump inhibitor (PPI), amoxicillin, and clarithromycin (1–5).

What drugs are in triple therapy for H. pylori?

Background: Triple therapy (proton pump inhibitor, clarithromycin and amoxicillin or an imidazole) is the first-line treatment for Helicobacter pylori infection. However, the effectiveness of triple therapy is decreasing due to the increase in antibiotic resistance.

How long do you give triple therapy for H. pylori?

The Experts recommend giving triple therapy regimens as first-line eradication therapy for Helicobacter pylori infection. The recommended duration of triple therapy is 10-14 days. However, recent studies suggest triple therapy with longer duration will provide a higher percentage of eradication.

How successful is triple therapy for Helicobacter?

Proton pump inhibitor–based triple-therapy regimens were significantly more effective than all other treatment regimens combined (87% vs 70%; P=. 001) in eradicating H pylori.

Should H. pylori therapy be continued for 7 14 days?

H. pylori eradication success rates were less than 80% for 7-day and 14-day treatment in ITT and PP analysis, indicating that both may be unsuitable for first-line therapy. Guidelines from the Korean Society of Gastroenterology suggest STT for 7–14 days as first-line therapy.

What is the new treatment for H. pylori?

So it’s good news that this week, the FDA approved a new drug, Talicia, to treat H. pylori infections. This new medication has been shown to be safe and more effective than other antibiotics like clarithromycin (Biaxin), metronidazole (Metrocream, Flagyl), and levofloxacin (Levaquin).

Do I have to take omeprazole for H. pylori?

H. pylori–positive and –negative GERD patients require the same dose of omeprazole during long-term maintenance treatment.

Does triple therapy for H. pylori work?

The recommended standard triple therapy for Helicobacter pylori infection, consisting of a proton pump inhibitor, clarithromycin and amoxicillin or metronidazole, can reach eradication rates in over 90%.