What is the best treatment for H. pylori related peptic ulcer disease?

STANDARD TRIPLE THERAPY A seven- to 10-day triple drug regimen consisting of a PPI, amoxicillin 1 g, and clarithromycin 500 mg (Biaxin) twice daily has long been the first-line therapy to eradicate H. pylori.

Why does H. pylori protect against GERD?

The most likely mechanism whereby H. pylori infection protects against GERD is by decreasing the potency of the gastric refluxate in patients with corpus predominant gastritis. A variety of implications of H. pylori infection on GERD treatment have also arisen in recent years.

Does H. pylori reduce stomach acid?

pylori attacks the lining that protects your stomach. The bacteria makes an enzyme called urease. This enzyme makes your stomach acids less acidic (neutralizes them). This weakens your stomach’s lining.

Is acid reflux a symptom of H. pylori?

Based on the findings of this study, significant evidence suggests the potential role of Helicobacter pylori infection in the development of gastroesophageal reflux disease.

What are the signs and symptoms of H. pylori?

Symptoms

  • An ache or burning pain in your stomach (abdomen)
  • Stomach pain that may be worse when your stomach is empty.
  • Nausea.
  • Loss of appetite.
  • Frequent burping.
  • Bloating.
  • Unintentional weight loss.

Does omeprazole make H. pylori worse?

They postulate that the severity of H pylori induced corpus gastritis is exacerbated by omeprazole; this would lead to decreased acid secretion and increased pH.

Does H. pylori cause mucus in throat?

Reported symptoms include cough, globus sensation, sore throat, hoarseness, excessive throat clearing, heartburn, dysphagia, and regurgitation. They are likely due to acid and mucus production.

Does H. pylori cause chest tightness?

There is a relationship between a peptic ulcer and H. pylori, where no serious infection causes peptic ulcers, and the chest pain associated with the H. pylori is associated with peptic ulcers.