What is the antidote for succinylcholine?

Dantrolene is an effective antidote.

Can you Redose succinylcholine?

Paralysis lasts for 3-8 minutes. If redosing of succinylcholine is required, it is suggested that the maximum safe cumulative dose of succinylcholine is 6 mg/kg. Systemic uptake, time to onset of action, and duration of action will be variable depending on the patient’s hemodynamic state and ability to absorb.

How is succinylcholine apnea treated?

Every apnea over 15 minutes requires maximal attention of the anesthesiologist. First it is necessary to eliminate other possible causes of apnea. The therapy is based on oxygenation with 100% O2 blood transfusion or transfusion of fresh frozen plasma or preparation of human acetylcholinesterase.

What is Anectine used for?

Anectine (succinylcholine chloride) is a skeletal muscle relaxant for intravenous (IV) administration indicated as an adjunct to general anesthesia, to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Does neostigmine work on succinylcholine?

It is concluded that succinylcholine-induced phase II block can be safely and rapidly antagonized with neostigmine.

What is neostigmine an antidote for?

Neostigmine is used as an antidote for anticholinergic intoxication. It is also used as a treatment for myasthenia gravis, treatment (antidote) for neuromuscular blockade, and treatment for ileus.

Can you give succinylcholine twice?

A longer-acting paralytic affords us time to secure the airway even in the more difficult cases without sending a nurse scrambling for a second dose of succinylcholine. Finally, repeat doses of succinylcholine increase the risk of its adverse effects (masseter spasm, hyperkalemia).

How much succinylcholine is lethal?

The 40-mg ampule dose of succinylcholine administered intramuscularly to the victims, possibly causing prolonged apnea, was considered to be at least around the minimum lethal dose, although the combined effect of the sedation with hypnotics also used was not negligible.

Can Edrophonium be given in succinylcholine apnea?

Edrophonium 10 mg, given 74 min after succinylcholine, when train-of-four stimulation was characteristic of phase II block, produced partial antagonism which was not sustained. Repeated doses of edrophonium to 70 mg and neostigmine to 2.5 mg did not antagonize or augment the block.

How do you reverse Suxamethonium?

Anticholinesterases reverse the effects of the non-depolarising (competitive) neuromuscular blocking drugs such as pancuronium bromide but they prolong the action of the depolarising neuromuscular blocking drug suxamethonium chloride.

What is Pavulon used for?

Pavulon (pancuronium bromide) Injection is a neuromuscular blocking agent used to provide skeletal muscle relaxation during tracheal intubation and surgery. Pavulon is available in generic form.

What is norcuron used for?

Vecuronium bromide, sold under the brand name Norcuron among others, is a medication used as part of general anesthesia to provide skeletal muscle relaxation during surgery or mechanical ventilation.