What is telomerase and its function?
What is telomerase and its function?
Telomerase is the enzyme responsible for maintenance of the length of telomeres by addition of guanine-rich repetitive sequences. Telomerase activity is exhibited in gametes and stem and tumor cells.
What is the role of telomerase in DNA replication quizlet?
telomerase adds DNA nucleotides to the overhang and DNA polymerase extends the complimentary strand.
What is the role of telomerase quizlet?
Telomerase allows for telomere length and equilibrium maintenance by adding on repeats to the end of the chromosome.
What is the function of the enzyme telomerase in eukaryotic DNA synthesis quizlet?
What is the function of the enzyme telomerase? Telomerase binds to telomeres and protects them from damage by shearing. Telomerase is a DNA repair enzyme that repairs telomere damage caused by UV light. Telomerase replicates telomere sequences at the end of chromosomes preventing telomere shortening.
Why do we need telomerase?
Telomeres act as protective caps on the ends of our chromosomes and prevent damage and fusion with other chromosomes. A useful analogy for this can be the way an aglet of a shoelace prevents fraying, unravelling and tangling of laces.
What would happen without telomerase?
Without telomerase activity, these cells would become inactive, stop dividing and eventually die. Drugs that inhibit telomerase activity, or kill telomerase-producing cells, may potentially stop and kill cancer cells in their tracks.
What is the RNA in telomerase doing?
Telomerase RNA is an essential core component of the telomerase ribonucleoprotein (RNP) enzyme that synthesizes telomeric sequences onto chromosome ends. Telomerase copies a short template sequence within the RNA component onto chromosome ends to counterbalance telomere shortening that occurs during DNA replication.
Which answer best describes the role of telomerase in replicating the ends of linear chromosomes?
Which answer best describes the role of telomerase in replicating the ends of linear chromosomes? It catalyzes the lengthening of telomeres, compensating for the shortening that could occur during replication without telomerase activity.
Is telomerase RNA transcribed DNA?
Telomerase RNA component, also known as TR, TER or TERC, is an ncRNA found in eukaryotes that is a component of telomerase, the enzyme used to extend telomeres. TERC serves as a template for telomere replication (reverse transcription) by telomerase….Mouse.
Ciliate telomerase RNA | |
---|---|
Domain(s) | Eukaryote |
PDB structures | PDBe |
What is telomerase made of?
Telomerase, also called telomere terminal transferase, is an enzyme made of protein and RNA subunits that elongates chromosomes by adding TTAGGG sequences to the end of existing chromosomes.