What is spironolactone 50mg used for?

Spironolactone is used in combination with other medicines to treat high blood pressure (hypertension) and heart failure. Lowering blood pressure can reduce the risk of strokes and heart attacks. Spironolactone is also used to lessen the need for hospitalization for heart failure.

What does spironolactone do to your body?

Spironolactone is a potassium-sparing diuretic (water pill). It prevents your body from absorbing too much salt and keeps your potassium levels from getting too low. This medicine is also used to treat or prevent hypokalemia (low potassium levels in the blood).

What are the side effects of spironolactone 50 mg?

Spironolactone side effects

  • diarrhea and abdominal cramping.
  • nausea and vomiting.
  • high potassium levels.
  • leg cramps.
  • headache.
  • dizziness.
  • drowsiness.
  • itching.

Is spironolactone tumorigenic?

However, spironolactone carries an official FDA warning regarding possible tumorigenicity. This warning is largely based on animal studies using doses up to 150 times greater than human doses and found in the development of hepatic, testicular, and breast adenomas.

Is spironolactone a tumorigen?

Orally administered Spironolactone has been shown to be a tumorigen in dietary administration studies performed in rats, with its proliferative effects manifested on endocrine organs and the liver.

What does spironolactone 50 mg look like?

Spironolactone 50 mg tablets are oval, white to off-white, scored, convex, coated, debossed with 853 left of the bisect on one side and debossed with “O” on the other side, supplied as: NDC Number

Are spironolactone and potassium canrenoate mutagenic?

In the absence of metabolic activation, neither Spironolactone nor potassium canrenoate has been shown to be mutagenic in mammalian tests in vitro.

What is spironolactone used to treat?

Spironolactone is indicated as add-on therapy for the treatment of hypertension, to lower blood pressure in patients who are not adequately controlled on other agents. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.