What is Regitine used for?

Regitine is indicated for the prevention or treatment of dermal necrosis and sloughing following intravenous administration or extravasation of norepinephrine. Regitine is also indicated for the diagnosis of pheochromocytoma by the Regitine blocking test.

What is phentolamine used to treat?

General information. Phentolamine is a non-selective alpha-adrenoceptor antagonist. It is used to treat hypertensive crises attributable to the effects of noradrenaline, as in pheochromocytoma and during the interaction of monoamine oxidase inhibitors with amine-containing medicaments and foods [1].

What drug class is phentolamine?

Phentolamine belongs to a group of medications called vasodilators.

What type of drug is Phenoxybenzamine?

Phenoxybenzamine belongs to the general class of medicines called antihypertensives. It is used to treat high blood pressure (hypertension) due to a disease called pheochromocytoma. Phenoxybenzamine blocks the effects of certain chemicals in the body.

How do you administer Regitine for extravasation?

Phentolamine (Regitine)2,5 Prepare by diluting 5 mg phentolamine in 10 mL of 0.9% sodium chloride. Inject subcutaneously into the extravasation area within 12 hours of extravasation. Blanching should reverse immediately; additional injections may be required if blanching returns.

Why is phentolamine used for erectile dysfunction?

Phentolamine given by injection causes blood vessels to expand, thereby increasing blood flow. When injected into the penis (intracavernosal), it increases blood flow to the penis, which results in an erection.

What is another name for phentolamine?

Phentolamine, sold under the brand name Regitine among others, is a reversible nonselective α-adrenergic antagonist.

What is phenoxybenzamine used for?

Phenoxybenzamine belongs to the general class of medicines called antihypertensives. It is used to treat high blood pressure (hypertension) due to a disease called pheochromocytoma.

Why is phenoxybenzamine used?

This medication is used to treat high blood pressure and heavy sweating due to a certain tumor of the adrenal glands (pheochromocytoma). Phenoxybenzamine belongs to a class of drugs known as alpha blockers. It works by relaxing and widening blood vessels so that blood can flow more easily.

What is the antidote for extravasation?

MANAGEMENT OF EXTRAVASATION. *No recommended antidote. †Recommended antidote: dexrazoxane or dimethyl sulfoxide (DMSO).