What is QTL mapping SlideShare?

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What is interval mapping?

Interval mapping is an extension of the individual marker analysis so that two markers are analyzed at a time. In the marker analysis (Chap. 8), we cannot estimate the exact position of a QTL. With interval mapping, we use two markers to determine an interval, within which a putative QTL position is proposed.

What is QTL mapping explain its importance with suitable example?

The primary purpose of QTL mapping is to localize chromosomal regions that significantly affect the variation of quantitative traits in a population. This localization is important for the ultimate identification of responsible genes and also for our understanding of genetic mechanisms of the variation.

What is QTL in plant breeding?

Quantitative trait loci (QTL) analysis allows the location and effect-estimation of the genetic elements controlling any trait by the joint study of segregation of marker genotypes and of phenotypic values of individuals or lines. QTL analysis is now seen as a procedure to fill the gap between “omics” and the field.

What is the difference between QTL and Gwas?

The key difference between QTL and GWAS relies on the type of sequences used in the analysis. QTL uses linkage gene loci to analyze phenotypic traits associated with polygenic inheritance while GWAS uses whole genome sequences to analyze single nucleotide polymorphisms of a particular condition.

What is LOD score in QTL mapping?

In interval mapping, the LOD score is log10 of the ratio of the probability that a QTL is present to the probability that a QTL is absent. For example, if the presence of a QTL is 1000 times more probable than its absence, then the LOD score = 3, because log10 of 1000 = 3.

What are the requirements for QTL mapping?

The requirements of QTL mapping are mapping population, saturated linkage map, phenotypic screening and statistical package.

Why is QTL important?

QTL analysis allows researchers in fields as diverse as agriculture, evolution, and medicine to link certain complex phenotypes to specific regions of chromosomes. The goal of this process is to identify the action, interaction, number, and precise location of these regions.