What is periodate used for?

What is periodate used for?

Uses. Sodium periodate can be used in solution to open saccharide rings between vicinal diols leaving two aldehyde groups. This process is often used in labeling saccharides with fluorescent molecules or other tags such as biotin.

What are periodate reagents?

Periodate reagents are by far the most widely used reagent for oxidative fission of vicinal diols. The reactions are usually rapid, efficient, clean, specific, and quantitative. Periodic acid was before the first choice but because of its high acidity, it is not useful for broad synthetic applications.

How do you make sodium periodate solution?

Dissolve sodium periodate (NaIO4) (Sigma) in 500 ml of deionized water at a concentration of 0.03-M (6.42 g). Protect from light. 2. Dissolve dextran (Polysciences) of molecular weight between 10,000 and 40,000 in the sodium periodate solution with stirring.

Is sodium periodate toxic?

Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion of less than 150 gram may be fatal or may produce serious damage to the health of the individual.

Is periodate an oxidizing agent?

Oxidation reactions Periodates are powerful oxidising agents.

Is sodium periodate soluble in water?

Solubility : Soluble in water (144 mg/ml at 25° C), sulfuric, nitric, and acetic acids. Melting Point : 300° C (dec.)

What is the name of NaIO?

Sodium hypoiodite
Sodium hypoiodite | NaIO – PubChem.

What is periodate anion?

Periodate is a monovalent inorganic anion obtained by deprotonation of periodic acid. It is a monovalent inorganic anion and an iodine oxoanion. It is a conjugate base of a periodic acid.

What is the charge of periodate?

-1
3.1Computed Properties