What is Pericentric chromatin?

Pericentric chromatin spans the distance between clusters of 16 bi-oriented kinetochores, resulting in a cylindrical array of the 32 pericentric regions within the mitotic spindle (Fig. 6B). This results in a cruciform configuration between sites of microtubule attachment and sister chromatid pairing (Fig.

What is Chroma in chromosome?

Chromatin fibers are tightly wound nucleosomes. Chromosomes are condensed chromatin fibers that are present inside the nucleus. During cell division, each chromatid replicates to form an X-shaped structure. In mitosis, each chromosome splits up from the centromere and moves towards the pole.

What is Pericentric?

involving sections of chromosome on both sides of the centromere; of or pertaining to the centromere of a chromosome.

What is Pericentromeric region of chromosome?

A larger pericentromeric region containing repetitive sequences and transposable elements surrounds the centromere that adopts a particular chromatin state characterized by specific histone variants and post-translational modifications and forms a transcriptionally repressive chromosomal environment.

What is heterochromatin and euchromatin?

Heterochromatin is defined as the area of the chromosome which is darkly stained with a DNA specific stain and is in comparatively condensed form. Euchromatin is defined as the area of the chromosome which is rich in gene concentration and actively participates in the transcription process.

What is Nonsister chromatid?

Non-sister chromatids are chromatids of homologous chromosomes. During cell division each chromosome needs to replicate, this ensures that the each daughter cell gets a complete set of chromosomes, which produces sister chromatids.

What is euchromatic region in chromosome?

Euchromatin is the genetically active region of the chromosome. It contains structural genes that are replicated during G1 and S phase of interphase by allowing polymerases to access the genes. 1.

What is Hetero and euchromatin?

Definition. Heterochromatin and euchromatin are two major categories of chromatin higher order structure. Heterochromatin has condensed chromatin structure and is inactive for transcription, while euchromatin has loose chromatin structure and active for transcription.

Why the DNA is coiled?

DNA molecules carry genetic instructions for our cells. Most of the time that DNA is tightly coiled around proteins. A new study shows that the coiled DNA acts much like the string on a yo-yo. And that’s good, because by being rolled up, each cell can store a lot of instructions.

What is Paranemic and Plectonemic?

Plectonemic coiling takes place during mitosis, in which sister chromatids are tightly coiled upon each other and are not easy to separate. Paranemic coiling found in meiosis where the two strands are loosely coiled, making them easier to separate.