What is normal range for tTG IgA test?
What is normal range for tTG IgA test?
Table 1.
| ANTIGEN | ANTIBODY TYPE | SENSITIVITY, % (RANGE) |
|---|---|---|
| Gliadin | IgG | 80 (42–100) |
| Endomysium | IgA | 95 (86–100) |
| IgG | 80 (70–90) | |
| Tissue transglutaminase | IgA | 98 (78–100) |
What is a high tTG IgA level?
Presence of the tissue transglutaminase (tTG) IgA antibody is associated with glutensensitive enteropathies such as celiac disease and dermatitis herpetiformis. tTG IgA antibody concentrations greater than 40 U/mL usually correlate with results of duodenal biopsies consistent with a diagnosis of celiac disease.
What is tTG IgA test?
What Is a Tissue Transglutaminase IgA (tTG-IgA) Test? A tissue transglutaminase IgA (tTg-IgA) test is used to help doctors diagnose celiac disease. In this autoimmune disorder, the immune system mistakenly thinks that gluten — a protein in wheat, barley, rye, and oats — is a foreign invader.
What is a low tTG IgA level?
Results: The overall prevalence of IgA deficiency was found to be very low with only 0.9% of individuals affected. Using receiver operating characteristic curve analysis we identified a cut-off value for tTG IgA of ≥0.10 μ/mL to be predictive for the absence of total IgA deficiency (IgA<0.06 g/L).
What is a positive result for celiac disease?
All celiac disease blood tests require that you be on a gluten-containing diet to be accurate. The tTG-IgA test will be positive in about 93% of patients with celiac disease who are on a gluten-containing diet. This refers to the test’s sensitivity, which measures how correctly it identifies those with the disease.
Is IgA high or low in celiac disease?
Immunoglobulin A (IgA) deficiency is 10 to 15 times more common in patients with celiac disease (CD) than in healthy subjects. Serological tests have become the preferred methods of diagnosing CD in both symptomatic and asymptomatic patients.
What is a low tTg IgA level?
