What is leukocyte nadir?

While the term nadir is used in reference to all blood cell counts, the concern during nadir is the drop in white blood cells, since they help your body fight infection. After the nadir, your blood cell count will start to rise, decreasing the risk of danger and recovering to a safe level before your next treatment.

What is the nadir value?

Nadir is a term that refers to the lowest point of anything. In medical terms, nadir could mean the lowest concentration of a drug in the body. With regard to chemotherapy specifically, it describes the point at which blood cell counts are at their lowest after a chemotherapy treatment.

What is Neutropenia nadir?

During cytotoxic chemotherapy, neutropenia typically occurs during the nadir—the lowest value to which the neutrophil count will fall following drug administration. The nadir typically occurs 10 to 14 days following chemotherapy administration during each treatment cycle.

What is a nadir period?

What Is Nadir? When discussing chemotherapy side effects often you will hear the word nadir, mainly in reference to the blood counts, particularly white blood cell count and platelet count. Nadir basically means low point, however further explanation may clarify this term in connection with chemotherapy treatment.

What does nadir mean in medical terms?

Nadir: The lowest point. The nadir may refer, for example, to the lowest blood count after chemotherapy or the lowest concentration of a drug in the body.

What is the nadir for Taxol?

Hematologic Effects Thrombocytopenia occurs less commonly than neutropenia. Conventional paclitaxel: Neutrophil nadir at day 10–12, return to baseline by day 15–21. Platelet nadir at day 8–9.

What is the nadir for Carboplatin?

The nadir usually occurs about day 21 in patients receiving single-agent therapy. By day 28, 90% of patients have platelet counts above 100,000/mm³; 74% have neutrophil counts above 2,000/mm³; 67% have leukocyte counts above 4,000/mm³.

What is zenith and nadir?

nadir, a term used in astronomy for the point in the heavens exactly opposite to the zenith, the zenith and nadir being the two poles of the horizon. That is, the zenith is directly overhead, the nadir directly underfoot. nadir. Related Topics: zenith celestial sphere.

How long is the nadir period?

The nadir of American race relations was the period in African-American history and the history of the United States from the end of Reconstruction in 1877 through the early 20th century when racism in the country was more open and pronounced than it had been during any other period in the nation’s history.

What is nadir after chemo?

Severe medullary aplasia in patients after receiving a chemotherapy cycle. It occurs at 7-14 days after undergoing a cycle due to cessation of normal production of blood cells (WBC, platelets, etc.), which increases the bleeding and/or infection risk.