What is lacosamide used for?

Lacosamide is used to treat partial-onset seizures. It is also used with other medicines to treat primary generalized tonic-clonic seizures. It acts on the central nervous system (CNS) to reduce the number and severity of seizures.

What is the mechanism of action of lacosamide?

Lacosamide has a novel mechanism of action of modulation of voltage-gated sodium channels by selective enhancement of slow inactivation but without apparent interaction with fast inactivation gating.

Can lacosamide be given IV?

in the treatment of primary generalised tonic-clonic seizures in adults, adolescents and children from 4 years of age with idiopathic generalised epilepsy. Lacosamide therapy can be initiated with either oral or intravenous administration.

Which medication would the nurse expect to administer for a patient with status epilepticus?

Lorazepam is considered the benzodiazepine of choice for the treatment of individual seizures and SE.

Is lacosamide a sedative?

One hundred and ninety three patients (48.7%) reported adverse effects (AEs). The most frequent were sedation and dizziness, followed by nausea. Lacosamide was discontinued in 150 patients (38%), 60 due to AEs alone.

What is another name for lacosamide?

Lacosamide (la-COS-a-mide) is the generic name (non-brand name) for the brand drug called Vimpat (VIM-pat) from UCB. It is available in tablet form, a liquid solution, and a liquid for injection. Lacosamide is available in many countries, but the name or look may be different.

How is lacosamide given?

Lacosamide injection comes as a solution (liquid) to be given intravenously (into a vein). It is usually injected slowly over a period of 30 to 60 minutes in children and adults, or over 15 minutes in adults if necessary.

What is the first line drug in the management of status epilepticus?

The first-line treatment for early SE mainly comprises the administration of benzodiazepines, the most frequently used of which include diazepam, lorazepam, and midazolam.

Which of the following is the first drug of choice for status epilepticus?

Diazepam. Diazepam is one of the drugs of choice for first-line management of status epilepticus.