What is Erbitux used to treat?

Cetuximab is used to treat a certain type of cancer of the colon (large intestine) or rectum. This medication is also used to treat head and neck cancer. Cetuximab works by slowing or stopping the growth of cancer cells.

What is cetuximab approved for?

Cetuximab is an epidermal growth factor receptor (EGFR) inhibitor with the following FDA-approved indications: colorectal cancer, metastatic, KRAS wild-type (without mutation), and head and neck cancer (squamous cell).

How long is Erbitux effective?

Overall survival in people who received ERBITUX with FOLFIRI was 19.6 months compared to 18.5 months, which was not significantly different.

What type of cancer is cetuximab used for?

Cetuximab is a type of targeted cancer drug. It is also known by its brand name Erbitux. You might have it as a treatment for advanced bowel cancer and head and neck cancers that start in the mouth and throat.

How often is Erbitux given?

HOW TO USE: Cetuximab is given by injection into a vein as directed by your doctor, usually once every week or every 2 weeks by a healthcare professional. Another drug (such as diphenhydramine) may be given before you receive cetuximab to lessen the chance of certain side effects.

When is cetuximab used?

Cetuximab is used with or without radiation therapy to treat a certain type of cancer of the head and neck that has spread to nearby tissues or other parts of the body.

Is Erbitux a monoclonal antibody?

Cetuximab (Erbitux) is one of the first EGFR monoclonal antibodies studied in OSCC. In clinical studies, cetuximab has demonstrated anti-tumor effects both as a single agent and when combined with radiation therapy or chemotherapy.

How successful is cetuximab?

Cetuximab also has activity as monotherapy in patients with recurrent and/or metastatic SCCHN who had failed platinum-based chemotherapy,. with a 12.6% response rate, disease control rate of 46%, and median response duration of ~ 6 months.

Do you lose your hair with Erbitux?

ERBITUX may cause hair changes. Hair changes during EGFR treatment may: Make the eyelashes grow very fast and become very long and bother your eyes. Cause fast growth to eyebrows.

Can Erbitux cure cancer?

Erbitux Offers ‘cure’ Potential To 3 Out Of 4 Advanced Colon Cancer Patients – But Conditions Apply. Researchers have narrowed down the conditions in metastatic colorectal cancer (mCRC) where treatment with the targeted biologic therapy Erbitux (cetuximab) is most likely to succeed.

What drug class is Erbitux?

This medication is classified as a “monoclonal antibody” and “Epidermal Growth Factor Receptor (EGFR) Inhibitor.” (For more detail, see “How this drug works” section below).

Is cetuximab chemotherapy or immunotherapy?

Immunotherapy with monoclonal antibodies, such as avelumab and cetuximab, may help the body’s immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.