What is EDTA in pharmacy?

Edetate disodium (EDTA) is a chelating (KEE-late-ing) agent. A chelating agent is capable of removing a heavy metal, such as lead or mercury, from the blood. EDTA is used to lower blood levels of calcium when they have become dangerously high.

What is EDTA solution used for?

In manufacturing, EDTA is used to improve stability of some pharmaceutical products, detergents, liquid soaps, shampoos, agricultural chemical sprays, contact lens cleaners and cosmetics. It is also used in certain blood collection tubes used by medical laboratories.

What is EDTA used for in pharmaceutical formulations?

Ethylenediaminetetraacetic acid (EDTA) is widely used in pharmaceutical industry as antioxidant, chelating agent for heavy metals, and preservative in many pharmaceutical formulations.

How do you make a standard EDTA solution?

EDTA Solution Preparation Weigh out approximately 2 g of reagent grade disodium EDTA into a 250 mL beaker. Add 0.05 g magnesium chloride hexahydrate, three pellets of NaOH and add about 200 mL of distilled water to dissolve. The EDTA will dissolve slowly over a period of a half an hour.

What is EDTA additive?

Calcium disodium EDTA is a common food additive and an ingredient in cosmetic and industrial products. It’s used in food to preserve flavor, color and texture. However, like many food additives, it has become quite controversial.

How do you make 0.1 mm EDTA?

Preparation and Standardization of 0.1 M Disodium Edetate (EDTA)

  1. Take about 100 ml of water in a cleaned and dried 1000 ml volumetric flask.
  2. Add about 37.2 gm of Disodium Edetate with continues stirring.
  3. Add more about 700 ml of water mix.
  4. Make up the volume 1000 ml with water.

How do you dissolve EDTA in water?

its very simple to dissolve EDTA in water just put the water and desired quantity of EDTA in glass bottle and put it on magnetic stirrer for some time it will dissolve it.

How do you administer EDTA?

EDTA is poorly absorbed through the gastrointestinal tract and therefore is administered through intramuscular injection or intravenous infusion. Due to side effects, chelation therapy is generally not used in adults with lead levels less than 45mcg/dl.