What is cimetidine 400mg used for?

Cimetidine is a histamine H2-receptor antagonist which rapidly inhibits both basal and stimulated gastric secretion of acid and reduces pepsin output. It is a reversible, competitive antagonist, and is used as an anti-ulcer drug.

What are the side effects of cimetidine 400 mg?

Common side effects of cimetidine include:

  • headache.
  • dizziness.
  • sleepiness.
  • enlarged breasts in men.
  • confusion (elderly)
  • impotence.
  • diarrhea.
  • nausea.

Why was cimetidine taken off the market?

The FDA said the medicines may contain “unacceptable” amounts of N-Nitrosodimethylamine (NDMA), a substance the World Health Organization has classified as a “probable human carcinogen.”

What is the side effect of cimetidine?

Headache, dizziness, drowsiness, or diarrhea may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects.

Is cimetidine the same as Zantac?

Cimetidine (Tagamet HB) is not the same as ranitidine (Zantac), but they are similar. They belong in the same drug class and lower the amount of acid in your stomach. Ranitidine (Zantac), is no longer available in the U.S. so cimetidine (Tagamet HB) can be a good replacement option.

Does cimetidine raise blood pressure?

Intracerebroventricular administration of cimetidine or metiamide (2 mumol/rat) increased the blood pressure and heart rate. It is concluded that the hypotension after i.v. cimetidine is mediated by peripheral mechanisms.

Is cimetidine safe to take?

Do not take over-the-counter cimetidine for longer than 2 weeks unless your doctor tells you to. If symptoms of heartburn, acid indigestion, or sour stomach last longer than 2 weeks, stop taking cimetidine and call your doctor.

Has cimetidine been discontinued?

Federal Register :: Determination That TAGAMET (Cimetidine) Tablets and Other Drug Products Were Not Withdrawn From Sale for Reasons of Safety or Effectiveness.

Is cimetidine safe?

Cimetidine is approved by the U.S. Food and Drug Administration (FDA) and is safe and effective when used according to the Drug Facts label.

Which is safer omeprazole or cimetidine?

Conclusion: Omeprazole 10 mg o.m. is more effective than cimetidine 800 mg nocte in the prevention of recurrence of GERD-associated heartburn and the occurrence of underlying oesophagitis.

Can cimetidine cause heart problems?

Concurrent administration of cimetidine and nifedipine may result in alterations in heart rate and blood pressure. The mechanism is inhibition of oxidative liver metabolism.

Is cimetidine 400 mg over-the-counter?

Cimetidine (Tagamet HB) is available both over-the-counter (OTC) and by prescription. The OTC strength is 200 mg, and the prescription strengths include 200 mg, 300 mg, 400 mg, and 800 mg. OTC dosing: Heartburn symptoms: The typical dose is 200 mg by mouth once a day.