What is cause of thalassemia?

Thalassemia is caused by mutations in the DNA of cells that make hemoglobin — the substance in red blood cells that carries oxygen throughout your body. The mutations associated with thalassemia are passed from parents to children.

Why is thalassemia called Cooley anemia?

Thalassemia major or Cooley anemia is one of the common monogenic hereditary hemoglobin disorders. It results from the absence of a beta-globin chain in the pathway of hemoglobin production. It is now a global public health concern due to changing demographics.

Can thalassemia minor get married?

No two Thalassemia minor patients should be allowed to marry.

How long do thalassemia patients live?

Survival of thalassemia patients The cumulative survival rate from birth until 10 years old was 99%. After reaching the age of 20 years, 88% of the patients survived until 30 years, 74% survived until 45, 68% survived until 50, and 51% survived until 55 years old.

Why is thalassemia common in Asia?

Due to high rate of international migration, thalassemias are spreading to non-endemic parts of the world [2]. In many Asian countries, the most common form of thalassemia results from the coinheritance of beta thalassemia and HbE.

What does Thalassaemia mean?

Thalassaemia is the name for a group of inherited conditions that affect a substance in the blood called haemoglobin. People with thalassaemia produce either no or too little haemoglobin, which is used by red blood cells to carry oxygen around the body. This can make them very anaemic (tired, short of breath and pale).

Can you have kids if you have thalassemia?

Can You Get Pregnant With Beta Thalassemia? Yes, but you may need help getting pregnant. Often, women with beta thalassemia will need to use medications to help them ovulate in order to become pregnant. Many health problems caused by beta thalassemia have to do with too much iron in your body.

Can 2 thalassemia patients marry?

When two such thalassaemia carriers marry and plan to have children there is a one-in-four chance of having a thalassaemic baby at every conception. A simple blood test for thalassaemia before marriage will let couples know if they are carriers or not. If both are non-carriers, they need not worry.