What is borderline in cancer?

A borderline tumor, sometimes called low malignant potential (LMP) tumor, is a distinct but yet heterogeneous group of tumors defined by their histopathology as atypical epithelial proliferation without stromal invasion.

Can you have borderline cancer?

Borderline tumours arise from the same type of cells, but their growth is much more controlled, and they are usually not able to spread. Most cases of ordinary ovarian cancer are found at an advanced stage (stage 3 or 4). This is when the cancer has spread beyond the ovary.

Can borderline tumors turn into cancer?

Borderline ovarian tumors (BOTs) are abnormal cells or growths that develop in the tissue encapsulating an ovary. While BOTs are not cancerous, they have the potential to develop into cancer. As such, doctors typically recommend surgery to remove these tumors.

Is a borderline tumor benign?

Borderline ovarian tumors, often referred to as “low malignant potential” tumors, are not invasive but also not completely benign. Their behavior can also vary based on microscopic features, and some are more likely to recur or spread than others.

Do you stage borderline tumors?

Preoperatively, borderline tumors are often presumed to be either benign or malignant ovarian masses; however, as with other ovarian masses, staging is performed surgically. Many sources recommend complete staging if a borderline tumor is found.

What is a good CA-125 number?

Generally speaking, the normal range of CA-125 is considered to be 0-35 units/mL, while a level above 35 units/mL is considered to be a high CA-125 level.

Is borderline ovarian cancer hereditary?

Many studies of BOT are ongoing, but few are evaluating the hereditary risk. Our study reveals a potential hereditary risk of cancer among BOT patients and suggests that between 3% and 19% of patients may need genetic counseling and confirmative testing.

What is serous borderline tumor?

Ovarian serous borderline tumor (SBT) is a low grade epithelial neoplasm of generally younger women with a favorable prognosis when diagnosed at an early stage. Defined, nonobligate precursor to low grade serous carcinoma (LGSC)

Do borderline tumors spread?

When borderline tumors spread, the can form tumor implants (deposits) on the peritoneum (lining of the abdomen) and on the surface of organs in the abdomen and pelvis. Most often, these implants are non-invasive, meaning they haven’t grown into the abdominal lining or organs.

What should my CA 125 level be?

How accurate is the CA 125 blood test?

Results: Using a CA125 cutoff of 30 U/mL, an overall sensitivity of 94.8% (96.6% specificity) was obtained when comparing malignancies versus healthy postmenopausal controls, whereas a cutoff of 65 U/mL provided a sensitivity of 83.9% (99.6% specificity).