What is an immunomodulatory agent?

(IH-myoo-noh-MOD-yoo-lay-ting AY-jent) A substance that stimulates or suppresses the immune system and may help the body fight cancer, infection, or other diseases. Specific immunomodulating agents, such as monoclonal antibodies, cytokines, and vaccines, affect specific parts of the immune system.

What drugs are immunomodulatory agents?

Thalidomide, lenalidomide, and pomalidomide Thalidomide (Thalomid), lenalidomide (Revlimid), and pomalidomide (Pomalyst) are known as immunomodulating drugs (or IMiDs).

What are the types of immunomodulators?

With respect to the different types of immunomodulators, they can be roughly divided into four categories: checkpoint inhibitors, cytokines, agonists, and adjuvants.

  • Checkpoint Inhibitors.
  • Cytokines.
  • Agonists.
  • Adjuvants.

What is meant by immunomodulation?

Listen to pronunciation. (IH-myoo-noh-MAH-juh-LAY-shun) Change in the body’s immune system, caused by agents that activate or suppress its function.

What is the difference between immunostimulant and immunomodulatory agent?

Immunomodulators are natural or synthetic substances that modulate or modify the immune response. They help regulate or normalize the immune system by either stimulating or suppressing the immune system. Immunostimulants, such as vaccines and interferons, enhance the body’s resistance against infections.

What is the difference between immunomodulation and immunosuppression?

Immunosuppressants inhibit the immune response in organ transplantation and autoimmune diseases, whereas immunostimulants increase the immune response in infections, immunodeficiency (for example AIDS) and cancers.

What is immunomodulation therapy?

Immunomodulatory therapy treats diseases that plague the human immune system. Monoclonal antibodies and other biologics response modifiers have allowed for targeted drug therapy in managing various autoimmune diseases.

What is the difference between immunomodulator and immunosuppressant?

In addition, although immunosuppressants appear to globally impair the host immune response typically in a dose-dependent fashion, immunomodulators may act more selectively by targeting only specific portions of the immune system and therefore pose a lower risk of complications related to immune dysfunction.

What are immunomodulatory actions?

Immunomodulatory drugs modify the response of the immune system by increasing (immunostimulators) or decreasing (immunosuppressives) the production of serum antibodies (1).

What is immune modulating?

Immune-modulating agents are a type of immunotherapy that enhance the body’s immune response against cancer. Types of immune-modulating agents include: Cytokines, which are proteins made by white blood cells.