What is an estrogen agonist antagonist?
What is an estrogen agonist antagonist?
Estrogen agonist/antagonists are used for fertility, breast cancer, PCOS, and osteoporosis. They work by changing hormone levels in the body.
What does estrogen receptor antagonist do?
Estrogen receptor antagonists bind to estrogen receptors and inhibit the action of estrogen. Estrogen controls the growth of certain types of breast cancers called estrogen receptor positive cancers. So estrogen receptor antagonists are useful in treating patients with estrogen sensitive breast cancers.
What hormone is estrogen antagonistic?
An example of such an estrogen antagonist is tamoxifen, which binds competitively to the estrogen receptor and alters the effectiveness of the hormone–receptor complex in regulating gene expression.
What is an estrogen receptor agonist?
Estrogen receptor (ER) agonists play crucial roles in the immune system and the CNS. Cell signaling pathways are modulated by ER agonists via binding to ERα and ERβ ER agonists can promote transcription of a large number of neuroprotective genes.
What are the two antagonistic hormones?
Calcitonin and PTH are referred to as antagonistic hormones, as their actions are diametrically opposite. While calcitonin is secreted when blood calcium level is extremely high, PTH is secreted when the blood calcium level is too low.
What are hormone antagonists explain?
Antagonistic hormones are a pair of hormones that have the opposite effects. For example, insulin and glucagon are antagonistic hormones because insulin functions to decrease blood glucose levels, whereas glucagon functions to increase blood glucose levels.
What type of receptor is estrogen receptor?
Estrogen receptors (ERs) are members of the superfamily class of nuclear receptors located in either the cell cytoplasm or nucleus and which function as transcription factors (Lovejoy, 2005).